Slager C J, Essed C E, Schuurbiers J C, Bom N, Serruys P W, Meester G T
J Am Coll Cardiol. 1985 Jun;5(6):1382-6. doi: 10.1016/s0735-1097(85)80352-1.
An alternative to the laser irradiation of atherosclerotic lesions has been developed. A pulsed electrocardiogram R wave-triggered electrical spark erosion technique is described. Controlled vaporization of fibrous and lipid plaques with minimal thermal side effects was achieved and documented histologically in vitro from 30 atherosclerotic segments of six human aortic autopsy specimens. Craters with a constant area and a depth that varied according to the duration of application were produced. The method was confirmed to be electrically safe during preliminary in vivo trials in the coronary arteries of seven anesthetized pigs. The main advantages of this technique are that it is simpler to execute than laser irradiation and potentially more controllable.
一种替代激光照射动脉粥样硬化病变的方法已经研发出来。本文描述了一种脉冲心电图R波触发的电火花侵蚀技术。该技术实现了对纤维斑块和脂质斑块的可控汽化，且热副作用极小，并在体外对6个人类主动脉尸检标本的30个动脉粥样硬化节段进行了组织学记录。产生了面积恒定、深度随作用时间变化的凹坑。在7只麻醉猪的冠状动脉中进行的初步体内试验证实了该方法在电方面的安全性。该技术的主要优点是比激光照射操作更简单，且可能更易于控制。
