Koszarny Arkadiusz, Górak Anna, Majdan Maria
Klinika Reumatologii i Układowych Chorób Tkanki Łącznej, Uniwersytet Medyczny w Lublinie, Lublin, Polska.
Wiad Lek. 2019;72(9 cz 1):1687-1690.
Sjögren's syndrome is a systemic autoimmune disease characterized by exocrine glands damage, resulting in the development of dry eyes and dry mouth, as well as extraglandular manifestation. It usually starts between the ages of 30 and 50. Late-onset Sjögren's syndrome should be considered as a disease that appears after age 65, but the literature also reports of the age 50, 60, or even 70. The prevalence of late-onset Sjögren's syndrome is estimated about 20%. The course of late-onset Sjögren's syndrome may differ when compared with patients with a younger onset. Lack of sicca symptoms and marker antibodies may be associated with a delay in Sjögren's syndrome diagnosis. Particularly in the elderly, the occurrence of sicca symptoms may be considered as age-related and medication-related.
干燥综合征是一种全身性自身免疫性疾病，其特征为外分泌腺受损，导致干眼症和口干症以及腺体外表现。它通常在30至50岁之间发病。迟发性干燥综合征应被视为65岁以后出现的疾病，但文献中也有50岁、60岁甚至70岁发病的报道。迟发性干燥综合征的患病率估计约为20%。与发病年龄较轻的患者相比，迟发性干燥综合征的病程可能有所不同。缺乏干燥症状和标志物抗体可能与干燥综合征的诊断延迟有关。特别是在老年人中，干燥症状的出现可能被认为与年龄和药物有关。
