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超声引导下肉毒毒素治疗慢性足底筋膜炎的疗效。

Outcomes of Ultrasound-Guided Gastrocnemius Injection With Botulinum Toxin for Chronic Plantar Fasciitis.

机构信息

Department of Orthopedics, Akhtar Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Foot Ankle Int. 2020 Jan;41(1):63-68. doi: 10.1177/1071100719875220. Epub 2019 Oct 5.

Abstract

BACKGROUND

The objective of this study was to determine whether the injection of botulinum toxin A (BTA) in the medial head of the gastrocnemius muscle could yield improvements in function and disability in patients with chronic plantar fasciitis with follow-up 12 months after treatment.

METHODS

Thirty-two patients with chronic plantar fasciitis were included in the study and randomly allocated to the BTA and placebo groups. The visual analog scale (VAS) and American Orthopaedic Foot & Ankle Society (AOFAS) scores were used to evaluate pain levels pre- and postinjection as well as function of the foot, respectively. Patients were also asked to rate their treatment satisfaction 1 year after injection. The range of dorsiflexion was measured before and 12 months after the injection.

RESULTS

At the 12-month follow-up, the mean VAS decreased from 7.8 to 4 in the placebo group and from 8 to 0.33 in the BTA group. Furthermore, the mean AOFAS scores increased from 48.4 to 65.3 in the placebo group and from 45.5 to 90.6 in the BTA group. The postinjection scores in the BTA group were significantly higher than those in the placebo group ( < .001). Patient satisfaction in the BTA group was higher than that in the placebo group at the 12-month follow-up.

CONCLUSION

In patients with chronic plantar fasciitis, the use of BTA had a positive effect on improvement in pain and foot function 1 year after treatment.

LEVEL OF EVIDENCE

Level I, prospective randomized controlled trial.

摘要

背景

本研究旨在确定在慢性足底筋膜炎患者的腓肠肌内侧头肌中注射肉毒杆菌毒素 A(BTA)是否能在治疗后 12 个月的随访中改善功能和残疾。

方法

将 32 例慢性足底筋膜炎患者纳入研究,并随机分为 BTA 组和安慰剂组。视觉模拟评分(VAS)和美国矫形足踝协会(AOFAS)评分分别用于评估注射前后的疼痛水平和足部功能。患者还被要求在注射后 1 年评估治疗满意度。在注射前和注射后 12 个月测量背屈范围。

结果

在 12 个月的随访中,安慰剂组的 VAS 均值从 7.8 降至 4,BTA 组从 8 降至 0.33。此外,安慰剂组的 AOFAS 评分从 48.4 增至 65.3,BTA 组从 45.5 增至 90.6。BTA 组的注射后评分明显高于安慰剂组(<0.001)。BTA 组的患者满意度在 12 个月的随访中高于安慰剂组。

结论

在慢性足底筋膜炎患者中,BTA 的使用在治疗后 1 年对改善疼痛和足部功能有积极影响。

证据等级

I 级,前瞻性随机对照试验。

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