经阴道切除直肠间质瘤：病例报告及文献复习。
Transvaginal excision of rectal stromal tumors: case reports and a literature review.
机构信息
Department of Obstetrics and Gynecology, Shengjing Hospital, China Medical University, 36 San Hao Street, Heping District, Shenyang, 110004, Liaoning, China.
Department of Gastrointestinal Department, Shengjing Hospital, China Medical University, 36 San Hao Street, Heping District, Shenyang, 110004, Liaoning, China.
出版信息
World J Surg Oncol. 2019 Oct 6;17(1):164. doi: 10.1186/s12957-019-1703-8.
BACKGROUND
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Rectal locations are very rare, and minimally invasive surgery is a good choice for the treatment of rectal GISTs.
CASE PRESENTATION
Two women each had a mass located on the lower vaginal-rectal space as determined by transvaginal ultrasound (TV-US), pelvis MR imaging, and colonoscopy. The patients successfully underwent transvaginal excision. The spindle-shaped cells were found in pathological test. The immunohistochemical analysis showed that CD117 and Dog-1 were stained positively. These results confirmed the masses as GISTs. The postoperative period was uneventful without anal dysfunction. Two patients were received adjuvant treatment with imatinib after surgery.
CONCLUSION
Transvaginal excision could be a minimally invasive and safe alternative treatment in the management of rectal GISTs in lower locations.
背景
胃肠道间质瘤（GISTs）是胃肠道最常见的间叶性肿瘤。直肠部位非常罕见，对于直肠 GISTs 的治疗，微创手术是一个很好的选择。
病例介绍
两名女性均通过经阴道超声（TV-US）、骨盆磁共振成像（MR 成像）和结肠镜检查发现下阴道-直肠间隙有肿块。患者成功接受了经阴道切除术。病理检查发现梭形细胞。免疫组化分析显示 CD117 和 Dog-1 阳性染色。这些结果证实肿块为 GISTs。术后无肛门功能障碍等并发症。两名患者术后均接受了伊马替尼辅助治疗。
结论
经阴道切除可作为低位直肠 GISTs 的一种微创、安全的替代治疗方法。
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