Department of Obstetrics and Gynecology, Álvarez-Buylla Hospital, Mieres, Spain.
J Low Genit Tract Dis. 2012 Apr;16(2):158-61. doi: 10.1097/LGT.0b013e31823b52af.
To describe a rare case of gastrointestinal stromal tumor (GIST) outside the gastrointestinal tract and arising in the rectovaginal septum with literature review.
This study involved a 29-year-old woman, gravida 0, with a GIST presenting as an asymptomatic tumor in the rectovaginal septum. The tumor was excised locally, and the patient received imatinib as adjuvant therapy. She is free of disease 2 years after surgery.
To our knowledge, only 5 cases of GIST presenting as rectovaginal mass have been reported previously. Local excision is the definitive treatment and the use of imatinib shows promising results. Mitotic activity, cellularity, and necrosis are the main prognostic factors. Long-term follow-up is necessary.Different physicians involved in the evaluation of a mass arising in the rectovaginal septum should be alert of GIST as differential diagnosis, even in young women.
描述一例罕见的胃肠道外胃肠道间质瘤（GIST），发生于直肠阴道隔，同时进行文献复习。
本研究纳入了一位 29 岁、初产妇的女性患者，其直肠阴道隔存在 GIST 表现为无症状肿瘤。肿瘤局部切除，患者接受伊马替尼辅助治疗。术后 2 年患者无病生存。
据我们所知，之前仅有 5 例 GIST 以直肠阴道肿块为表现的病例报道。局部切除是明确的治疗方法，伊马替尼的应用显示出良好的效果。有丝分裂活性、细胞密度和坏死是主要的预后因素。需要长期随访。评估直肠阴道隔肿块的不同医生应警惕 GIST 作为鉴别诊断，即使是年轻女性。
