Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Rheumatology Unit, University of Florence, Italy.
Clin Exp Rheumatol. 2019 Jul-Aug;37 Suppl 119(4):3-14. Epub 2019 Oct 3.
Systemic sclerosis (SSc) is a complex disorder characterised by the involvement of small arteries, microvessels and connective tissue, with deposition of fibrotic tissue and microvascular obliteration in the skin and internal organs. Due to the multifaceted nature of the disease, several articles are published in the medical literature every year, aimed at exploring different aspects of the pathogenesis, internal organ involvement and clinical aspects, and possible therapeutic approaches. In this article we have reviewed the literature on SSc of the past year, with the aim of identifying novel approaches that may help the treating physician in the clinical management of patients.
系统性硬化症（SSc）是一种复杂的疾病，其特征为小动脉、微血管和结缔组织受累，皮肤和内脏器官中纤维组织沉积和微血管闭塞。由于疾病的多方面性质，每年都有许多文章在医学文献中发表，旨在探讨发病机制、内脏器官受累和临床方面的不同方面，以及可能的治疗方法。在本文中，我们回顾了过去一年中关于 SSc 的文献，目的是确定新的方法，以帮助治疗医生对患者进行临床管理。
