Devars du Mayne J F, Marche C, Penalba C, Vittecoq D, Saimot G, Cerf M
Presse Med. 1985 May 25;14(21):1177-80.
Liver biopsies were systematically performed in 20 patients with evidence of an acquired immunodeficiency syndrome (18 with opportunistic infections, 9 with Kaposi's sarcoma). Hepatitis, related to hepatitis-B virus in 3 cases and to cytomegalovirus in 3 cases, was present in 6 of them. All patients had at least one of the three following lesions: non-specific portal inflammatory infiltration (6 cases), granulomatous lesions (12 cases), vascular abnormalities (12 cases). Among hepatic granulomatous lesions: 3 were due to acid-fast bacilli and 1 to Cryptococcus. Sinusoidal abnormality included proliferation of Küpffer cells (9 cases), sinusoidal dilatation (2 cases), peliosis (4 cases) and Kaposi's sarcoma (1 case). A relationship between these abnormalities cannot be excluded.
对20例有获得性免疫缺陷综合征证据的患者进行了系统性肝活检（18例有机会性感染，9例有卡波西肉瘤）。其中6例存在肝炎，3例与乙型肝炎病毒相关，3例与巨细胞病毒相关。所有患者至少有以下三种病变中的一种：非特异性门静脉炎性浸润（6例）、肉芽肿性病变（12例）、血管异常（12例）。在肝脏肉芽肿性病变中：3例由抗酸杆菌引起，1例由隐球菌引起。窦状隙异常包括库普弗细胞增殖（9例）、窦状隙扩张（2例）、血囊肿（4例）和卡波西肉瘤（1例）。不能排除这些异常之间存在关联。
