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每年 PROSPERO 中注册的系统评价越来越多，但很少有记录的状态是最新的。

More systematic reviews were registered in PROSPERO each year, but few records' status was up-to-date.

机构信息

Faculty of Health, School of Medicine, Institute for Research in Operative Medicine, Witten/Herdecke University, Cologne, Germany.

Faculty of Health, School of Medicine, Institute for Research in Operative Medicine, Witten/Herdecke University, Cologne, Germany.

出版信息

J Clin Epidemiol. 2020 Jan;117:60-67. doi: 10.1016/j.jclinepi.2019.09.026. Epub 2019 Oct 4.

DOI:10.1016/j.jclinepi.2019.09.026
PMID:31589953
Abstract

OBJECTIVES

To determine the proportion of systematic reviews (SRs) registered in PROSPERO and explore differences between publication years, review focus, and country. Secondary objectives were (1) to compare the characteristics of registered and nonregistered SRs and (2) to assess the up-to-dateness of the PROSPERO records' status.

STUDY DESIGN AND SETTING

In November 2018, we searched PubMed for SRs that were eligible for registration in PROSPERO. We included a random sample of n = 500 SRs. Data were analyzed descriptively.

RESULTS

Overall, 76 (15.2%) of the included SRs had been registered in PROSPERO. This proportion has increased with each year, up to 31.6% (36/114) in 2018. It did not notably differ depending on the reviews' focus. SRs from the United States or China were generally registered less frequently and SRs from Australia or Canada more frequently. Registered and nonregistered SRs did not differ regarding the number of authors or the time from submission to publication or from search to submission and publication. We could analyze 75 PROSPERO records, of which 63 (84.0%) were not up-to-date. Most SRs (49/75; 65.3%) were still listed as "ongoing."

CONCLUSION

More SRs were registered in PROSPERO each year, but only few records' status was up-to-date.

摘要

目的

确定在 PROSPERO 中注册的系统评价（SR）的比例，并探讨其在出版年份、综述重点和国家方面的差异。次要目标是（1）比较已注册和未注册的 SR 的特征，（2）评估 PROSPERO 记录状态的最新程度。

研究设计和设置

在 2018 年 11 月，我们在 PubMed 中搜索符合 PROSPERO 注册条件的 SR。我们纳入了 n=500 篇随机样本的 SR。对数据进行描述性分析。

结果

总体而言，76 篇（15.2%）符合条件的纳入 SR 在 PROSPERO 中进行了注册。这一比例逐年增加，在 2018 年达到了 31.6%（36/114）。这与综述重点无关。来自美国或中国的 SR 通常注册频率较低，而来自澳大利亚或加拿大的 SR 注册频率较高。注册和未注册的 SR 在作者数量、从提交到出版的时间、从检索到提交和出版的时间方面没有差异。我们可以分析 75 个 PROSPERO 记录，其中 63 个（84.0%）的状态未更新。大多数 SR（49/75；65.3%）仍被列为“正在进行中”。

结论

每年在 PROSPERO 中注册的 SR 越来越多，但只有少数记录的状态是最新的。

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