University of Split School of Medicine, 21000 Split, Croatia.
Center for Evidence-Based Medicine & Health Care, Catholic University of Croatia, 10000, Zagreb, Croatia.
J Comp Eff Res. 2023 Mar;12(3):e220129. doi: 10.2217/cer-2022-0129. Epub 2023 Jan 23.
We analyzed characteristics and completion status of Systematic Reviews (SRs) about regional anesthesia for acute perioperative pain relief registered in PROSPERO. PROSPERO was searched on 5 January 2022. Characteristics of PROSPERO records, completion status and publication information were extracted. PubMed and Google Scholar were searched by 31 May 2022, for additional published SRs. The inconsistency of PROSPERO records' status was analyzed by comparing the most recent PROSPERO status with subsequent publication of completed SR. Time-to-publication was calculated. Almost half of 174 included PROSPERO records (49%) were registered in 2021. A median of 3 (IQR: 2-4.75) authors, and a search of 4 information sources (IQR: 3-5) was planned. At first registration, 51 (29%) records had already started or completed formal screening. PROSPERO records included mostly adults (48%) undergoing trunk blocks (56%), with pain intensity (74%) as a main outcome. 147 (84%) PROSPERO records had a status "ongoing". Yet, 71 (41%) PROSPERO records were completed SRs, published after a median of 291 days. Inconsistency in status was found in 34% of PROSPERO records. Despite an increase in PROSPERO registrations about regional anesthesia, most were not published, and a third had inaccurate status.
我们分析了 PROSPERO 中注册的关于区域麻醉用于急性围手术期疼痛缓解的系统评价（SRs）的特点和完成情况。于 2022 年 1 月 5 日在 PROSPERO 中进行了检索。提取了 PROSPERO 记录的特征、完成情况和出版信息。于 2022 年 5 月 31 日通过 PubMed 和 Google Scholar 进行了额外的已发表 SR 搜索。通过比较最近的 PROSPERO 状态和随后发表的已完成 SR 来分析 PROSPERO 记录状态的不一致性。计算了发表时间。174 项纳入的 PROSPERO 记录中，近一半（49%）是在 2021 年注册的。中位数为 3 位（IQR：2-4.75）作者，计划检索 4 个信息源（IQR：3-5）。在第一次注册时，有 51 项（29%）记录已经开始或完成了正式筛选。PROSPERO 记录主要包括接受躯干阻滞（56%）的成年人（48%），主要结局为疼痛强度（74%）。147 项（84%）PROSPERO 记录的状态为“进行中”。然而，有 71 项（41%）PROSPERO 记录是已完成的 SR，在中位数为 291 天后发表。在 34%的 PROSPERO 记录中发现了状态不一致。尽管 PROSPERO 中关于区域麻醉的注册数量有所增加，但大多数未发表，三分之一的记录状态不准确。
