Pediatric Department, University Hospital of Ioannina, Ioannina, Greece.
Nephrology Department, University Hospital of Ioannina, Ioannina, Greece.
J Pediatr Urol. 2019 Dec;15(6):598-603. doi: 10.1016/j.jpurol.2019.09.010. Epub 2019 Sep 16.
The aim of this study was to present updated information on clinical, laboratory, and imaging risk factors and predictors of renal scarring after first or recurrent febrile UTIs, which may be associated with renal scarring.
PubMed was searched for current data on possible risk factors and predictors of renal scarring after febrile urinary tract infections in children.
Recurrence of acute pyelonephritis is an independent risk factor for renal scarring, while the duration of fever before treatment initiation is mainly associated with acute pyelonephritis and its severity. Severe vesicoureteral reflux is an important independent risk factor for the development of renal scarring after a febrile urinary tract infection.
Certain clinical parameters could be used to identify children at high risk for renal scarring after febrile urinary tract infection, helping clinicians to reserve dimercaptosuccinic acid scan for selected cases.
本研究旨在介绍首次或反复发热性尿路感染后发生肾瘢痕的临床、实验室和影像学危险因素和预测因素的最新信息，这些因素可能与肾瘢痕有关。
在 PubMed 上搜索了有关儿童发热性尿路感染后发生肾瘢痕的可能危险因素和预测因素的最新数据。
急性肾盂肾炎的复发是肾瘢痕形成的独立危险因素，而治疗开始前发热的持续时间主要与急性肾盂肾炎及其严重程度有关。严重的膀胱输尿管反流是发热性尿路感染后发生肾瘢痕的重要独立危险因素。
某些临床参数可用于识别发热性尿路感染后发生肾瘢痕的高危儿童，帮助临床医生为选定病例保留巯基丁二酸扫描。
