成年胸腺切除对南非爪蟾（非洲爪蟾）辅助功能的影响。
The effect of adult thymectomy upon helper function in Xenopus laevis, the South African clawed toad.
作者信息
Gruenewald D A, Ruben L N
出版信息
Immunology. 1979 Sep;38(1):191-4.
Carrier-primed helper activity enhancing anti-hapten (TNP-) responses in young adult Xenopus laevis reached peak levels 2-4 days after a low dose challenge (0.005% RBC) of unconjugated carrier. It fell quickly to negligible levels by 10 days. Adult thymectomized (ATx) animals were consistently unable to generate substantial levels of hapten-specific antigen-binding spleen cell (ABC) activity. Since ATx does not severely reduce splenic ABC responses to the high dose (10% RBC) of carrier used for hapten challenge, the results suggested a role for Xenopus adult thymus in carrier-specific enhancement of an anti-hapten response.
在未结合载体的低剂量激发（0.005%红细胞）后2至4天，携带引发的辅助活性增强了非洲爪蟾幼蛙对抗半抗原（三硝基苯 - ）的反应，并达到峰值水平。到第10天时，其迅速降至可忽略不计的水平。成年胸腺切除（ATx）动物始终无法产生大量的半抗原特异性抗原结合脾细胞（ABC）活性。由于ATx不会严重降低脾脏对用于半抗原激发的高剂量（10%红细胞）载体的ABC反应，结果表明非洲爪蟾成年胸腺在抗半抗原反应的载体特异性增强中发挥作用。
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