NTT Hi-Tech Institute, Nguyen Tat Thanh University, Ho Chi Minh City, Vietnam.
Department of Biotechnology, Institute of Biotechnology and Food-technology, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Biol Cell. 2019 Nov;111(11):284-291. doi: 10.1111/boc.201900069. Epub 2019 Oct 24.
Active repressors have been evidenced to function in different plant growth and development programs including hormonal signalling pathways. In Arabidopsis, the MYB-bHLH-WDR (MBW) complex is known to regulate different phenotypic traits such as anthocyanin biosynthesis, seed coat colour, trichome and root hair patterning. A number of transcription factors have been identified to play a negative role in the regulation of these traits via the interruption of MBW formation and function. Since these transcription factors work to interfere with the MBW complex, this review suggests their general name as MBW interferers (MBWi). Recent studies have shed light on the molecular mechanism of these MBWi and this review is aiming to provide a precise view of these MBWi. Moreover, from these, a new characteristic of active repressors is also updated.
活性阻遏物已被证明在包括激素信号通路在内的不同植物生长和发育程序中发挥作用。在拟南芥中，已知 MYB-bHLH-WDR（MBW）复合物调节不同的表型特征，如花青素生物合成、种皮颜色、毛状体和根毛模式。已经鉴定出许多转录因子通过中断 MBW 的形成和功能在这些特征的调节中发挥负作用。由于这些转录因子通过干扰 MBW 复合物起作用，因此本综述建议将其统称为 MBW 干扰因子（MBWi）。最近的研究揭示了这些 MBWi 的分子机制，本综述旨在提供对这些 MBWi 的精确观察。此外，从这些研究中，还更新了活性阻遏物的一个新特征。
