Head and Neck Surgery and Otorhinolaryngology Department, A.C. Camargo Cancer Center , Sao Paulo , Brazil.
Head and Neck Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center , New York , NY , USA.
Expert Rev Anticancer Ther. 2019 Oct;19(10):899-908. doi: 10.1080/14737140.2019.1674143. Epub 2019 Oct 8.
: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. : We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. : Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities.
: 对于患有腮腺癌的临床颈部阴性(cN0)患者,其管理存在争议。治疗方案可包括观察、选择性颈部清扫术或选择性放射治疗。: 我们针对患有腮腺癌的 cN0 患者的治疗方案进行了探讨。通过文献回顾确定了这群患者的最佳治疗方案。: 患有腮腺癌且临床颈部阴性的患者有多种治疗选择。分析肿瘤分期、组织学和分级对于更好地确定隐匿性淋巴结转移风险患者至关重要。这些患者可通过手术、放疗或两者联合治疗,具体取决于危险因素的存在、这些危险因素被发现的时间、患者相关的临床情况、医疗服务提供者的专业知识和机构设施。