• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

靶向肌肉再支配技术在手部治疗指截肢后复发性症状性神经瘤中的新应用。

Novel Use of Targeted Muscle Reinnervation in the Hand for Treatment of Recurrent Symptomatic Neuromas Following Digit Amputations.

作者信息

Daugherty Timothy H F, Bueno Reuben A, Neumeister Michael W

机构信息

Institute for Plastic Surgery, Southern Illinois University School of Medicine, Springfield, Ill.

出版信息

Plast Reconstr Surg Glob Open. 2019 Aug 8;7(8):e2376. doi: 10.1097/GOX.0000000000002376. eCollection 2019 Aug.

DOI:10.1097/GOX.0000000000002376
PMID:31592032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6756639/
Abstract

Targeted muscle reinnervation (TMR) has been shown to decrease neuroma pain after major limb loss; however, it has not previously been described for the treatment of symptomatic neuromas in the hand after digit amputations. This report describes the use of TMR in the hand for treatment of a patient with recurrent neuromas after ray amputation of the index and long fingers that were refractory to traditional treatments. TMR was performed first for the superficial branch of the radial nerve 6 years ago to treat the dorsal neuroma pain. Following this, there was complete resolution on the dorsal aspect of the hand, however, continued neuroma pain on the volar aspect of the hand. This was treated more recently with excision of the neuromas and TMR to motor branches of the intrinsic muscles of the hand. Outcomes were measured with a numerical rating scale and Patient-Reported Outcomes Measurement System assessments and revealed decreased pain postoperatively and less interference of her activities due to pain. This report demonstrates the ability to perform TMR within the hand with good results when used for the treatment of symptomatic neuromas.

摘要

靶向肌肉再支配术(TMR)已被证明可减轻大肢体缺失后的神经瘤疼痛;然而,此前尚未有关于其用于治疗手指截肢后手的症状性神经瘤的描述。本报告介绍了TMR在手部的应用,用于治疗示指和中指射线截肢后复发性神经瘤且对传统治疗无效的患者。6年前首次对桡神经浅支进行TMR以治疗手背神经瘤疼痛。此后,手背疼痛完全缓解,但手掌仍持续存在神经瘤疼痛。最近通过切除神经瘤并对手部固有肌运动支进行TMR来治疗。通过数字评分量表和患者报告结局测量系统评估来衡量结果,结果显示术后疼痛减轻,疼痛对其活动的干扰减少。本报告证明了在手内进行TMR治疗症状性神经瘤时能取得良好效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/593da95f6983/gox-7-e2376-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/6ca25efc4bd1/gox-7-e2376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/d6c2acf4336e/gox-7-e2376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/b587a3167fd2/gox-7-e2376-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/593da95f6983/gox-7-e2376-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/6ca25efc4bd1/gox-7-e2376-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/d6c2acf4336e/gox-7-e2376-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/b587a3167fd2/gox-7-e2376-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64d0/6756639/593da95f6983/gox-7-e2376-g004.jpg

相似文献

1
Novel Use of Targeted Muscle Reinnervation in the Hand for Treatment of Recurrent Symptomatic Neuromas Following Digit Amputations.靶向肌肉再支配技术在手部治疗指截肢后复发性症状性神经瘤中的新应用。
Plast Reconstr Surg Glob Open. 2019 Aug 8;7(8):e2376. doi: 10.1097/GOX.0000000000002376. eCollection 2019 Aug.
2
Targeted Muscle Reinnervation in the Hand: An Anatomical Feasibility Study for Neuroma Treatment and Prevention.手部靶向肌肉神经再支配:神经瘤治疗和预防的解剖学可行性研究。
J Hand Surg Am. 2020 Sep;45(9):802-812. doi: 10.1016/j.jhsa.2020.04.019. Epub 2020 Jul 27.
3
Targeted Muscle Reinnervation at the Time of Amputation Decreases Recurrent Symptomatic Neuroma Formation.截肢时的靶向肌肉神经再支配可减少复发性症状性神经瘤的形成。
Plast Reconstr Surg. 2024 Jan 1;153(1):154-163. doi: 10.1097/PRS.0000000000010692. Epub 2023 May 18.
4
Practice Patterns and Pain Outcomes for Targeted Muscle Reinnervation: An Informed Approach to Targeted Muscle Reinnervation Use in the Acute Amputation Setting.靶向肌肉神经再支配的实践模式和疼痛结局:在急性截肢环境中靶向肌肉神经再支配使用的明智方法。
J Bone Joint Surg Am. 2021 Apr 21;103(8):681-687. doi: 10.2106/JBJS.20.01005.
5
Managing Major Peripheral Nerves in Forearm-Level Amputations With TMR and RPNI: What's the Best Recipe?运用靶肌肉神经转位术和股薄肌神经植入术处理前臂水平截肢中的主要周围神经:最佳方案是什么?
Hand (N Y). 2024 Sep 12:15589447241277842. doi: 10.1177/15589447241277842.
6
Targeted Muscle Reinnervation to Improve Pain, Prosthetic Tolerance, and Bioprosthetic Outcomes in the Amputee.靶向肌肉再支配以改善截肢者的疼痛、假肢耐受性和生物假肢效果。
Adv Wound Care (New Rochelle). 2017 Aug 1;6(8):261-267. doi: 10.1089/wound.2016.0717.
7
The effects of targeted muscle reinnervation on neuromas in a rabbit rectus abdominis flap model.靶向肌肉再支配对兔腹直肌皮瓣模型中神经瘤的影响。
J Hand Surg Am. 2012 Aug;37(8):1609-16. doi: 10.1016/j.jhsa.2012.04.044. Epub 2012 Jul 4.
8
Targeted Muscle Reinnervation in the Hand: A Technical Roadmap.手部靶向肌肉再支配:技术路线图。
J Hand Surg Am. 2022 Mar;47(3):287.e1-287.e8. doi: 10.1016/j.jhsa.2021.04.031. Epub 2021 Jun 9.
9
Targeted Muscle Reinnervation to Expendable Motor Nerves for the Treatment of Refractory Symptomatic Neuromas in Nonamputees.将可牺牲运动神经进行靶向肌肉再支配以治疗非截肢患者的难治性症状性神经瘤。
Plast Reconstr Surg Glob Open. 2021 Feb 16;9(2):e3436. doi: 10.1097/GOX.0000000000003436. eCollection 2021 Feb.
10
A Technical Guide for Sciatic Nerve Targeted Muscle Reinnervation in a Transfemoral Amputee.经股截肢患者坐骨神经靶向肌肉再支配技术指南
Plast Reconstr Surg Glob Open. 2022 Sep 28;10(9):e4525. doi: 10.1097/GOX.0000000000004525. eCollection 2022 Sep.

引用本文的文献

1
Targeted Muscle Reinnervation Using the Anterior Interosseous Nerve for Symptomatic Wrist Level Neuromas.使用骨间前神经进行靶向肌肉再支配治疗有症状的腕部水平神经瘤。
Hand (N Y). 2025 May 22:15589447251339506. doi: 10.1177/15589447251339506.
2
Targeted Muscle Reinnervation-an Up-to-Date Review: Evidence, Indications, and Technique.靶向肌肉再支配——最新综述:证据、适应症和技术
Arch Plast Surg. 2025 Apr 1;52(3):153-168. doi: 10.1055/a-2521-2199. eCollection 2025 May.
3
The Recurrence of Painful Neuromas of the Limbs Following TMR.

本文引用的文献

1
Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation.在大肢体截肢时,通过靶向肌肉神经再支配对幻肢和残肢痛进行预防性治疗。
J Am Coll Surg. 2019 Mar;228(3):217-226. doi: 10.1016/j.jamcollsurg.2018.12.015. Epub 2019 Jan 8.
2
Targeted Muscle Reinnervation Treats Neuroma and Phantom Pain in Major Limb Amputees: A Randomized Clinical Trial.靶向肌肉神经再支配治疗主要肢体截肢患者的神经瘤和幻肢痛:一项随机临床试验。
Ann Surg. 2019 Aug;270(2):238-246. doi: 10.1097/SLA.0000000000003088.
3
Symptomatic Neuroma Following Initial Amputation for Traumatic Digital Amputation.
胸廓出口减压术后肢体疼痛性神经瘤的复发
J Clin Med. 2025 Feb 8;14(4):1078. doi: 10.3390/jcm14041078.
4
Neuroma Analysis in Humans: Standardizing Sample Collection and Documentation.神经瘤分析在人类中:规范样本采集和文件记录。
J Surg Res. 2024 Jun;298:185-192. doi: 10.1016/j.jss.2024.03.019. Epub 2024 Apr 15.
5
Use of Supinator Motor Branches in Targeted Muscle Reinnervation of the Superficial Radial Nerve.旋后肌运动支在桡神经浅支靶向肌肉再支配中的应用。
Plast Reconstr Surg Glob Open. 2024 Jan 10;12(1):e5512. doi: 10.1097/GOX.0000000000005512. eCollection 2024 Jan.
6
Pronator Quadratus: A Preferable Recipient for Targeted Muscle Reinnervation of Neuromas in the Hand.旋前方肌:手部神经瘤靶向肌肉再支配的理想受体。
Plast Reconstr Surg Glob Open. 2022 Nov 18;10(11):e4640. doi: 10.1097/GOX.0000000000004640. eCollection 2022 Nov.
7
Impact of Timing of Targeted Muscle Reinnervation on Pain and Opioid Intake Following Major Limb Amputation.靶向肌肉再支配时机对大肢体截肢术后疼痛及阿片类药物摄入量的影响
Hand (N Y). 2024 Mar;19(2):200-205. doi: 10.1177/15589447221107696. Epub 2022 Jul 13.
8
Digital Nerve Management and Neuroma Prevention in Hand Amputations.手部截肢中的数字神经管理和神经瘤预防。
Hand (N Y). 2023 Jul;18(5):838-844. doi: 10.1177/15589447211065074. Epub 2022 Feb 8.
9
[Surgical management of peripheral nerves after extremity loss].[肢体缺失后周围神经的外科处理]
Orthopade. 2021 Jan;50(1):14-23. doi: 10.1007/s00132-020-04032-1.
10
Targeted muscle reinnervation for the management of pain in the setting of major limb amputation.靶向肌肉再支配用于治疗大肢体截肢后的疼痛。
SAGE Open Med. 2020 Sep 15;8:2050312120959180. doi: 10.1177/2050312120959180. eCollection 2020.
创伤性手指截肢初次截肢后出现症状性神经瘤
J Hand Surg Am. 2018 Jan;43(1):86.e1-86.e8. doi: 10.1016/j.jhsa.2017.08.021. Epub 2017 Sep 23.
4
Targeted muscle reinnervation: a novel approach to postamputation neuroma pain.靶向肌肉神经再支配:一种治疗截肢后神经瘤疼痛的新方法。
Clin Orthop Relat Res. 2014 Oct;472(10):2984-90. doi: 10.1007/s11999-014-3528-7.
5
Outcomes of the surgical treatment of peripheral neuromas of the hand and forearm: a 25-year comparative outcome study.手部和前臂周围神经瘤手术治疗的结果:一项25年的比较性结局研究。
Ann Plast Surg. 2013 Dec;71(6):654-8. doi: 10.1097/SAP.0b013e3182583cf9.
6
Neuromas of the hand and upper extremity.手部及上肢神经瘤
J Hand Surg Am. 2010 Mar;35(3):499-510. doi: 10.1016/j.jhsa.2009.12.019.
7
Relocation of painful neuromas in Zone III of the hand and forearm.手部和前臂Ⅲ区疼痛性神经瘤的移位
J Hand Surg Eur Vol. 2008 Apr;33(2):155-62. doi: 10.1177/1753193408087107.
8
The role of peripheral nerve surgery in the treatment of chronic pain associated with amputation stumps.周围神经手术在治疗与截肢残端相关的慢性疼痛中的作用。
Plast Reconstr Surg. 2008 Mar;121(3):908-914. doi: 10.1097/01.prs.0000299281.57480.77.
9
Relocation of painful end neuromas and scarred nerves from the zone II territory of the hand.将手部II区的疼痛性终末神经瘤和瘢痕化神经进行移位。
J Hand Surg Eur Vol. 2007 Feb;32(1):38-44. doi: 10.1016/j.jhsb.2006.10.013. Epub 2006 Nov 28.
10
Treatment of end-neuromas, neuromas-in-continuity and scarred nerves of the digits by proximal relocation.通过近端移位治疗指端神经瘤、连续性神经瘤和指部瘢痕化神经。
J Hand Surg Br. 2004 Aug;29(4):338-50. doi: 10.1016/j.jhsb.2004.01.005.