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[肢体缺失后周围神经的外科处理]

[Surgical management of peripheral nerves after extremity loss].

作者信息

Gstoettner Clemens, Laengle Gregor, Salminger Stefan, Festin Christopher, Platzgummer Hannes, Aszmann Oskar C

机构信息

Klinisches Labor für Bionische Extremitätenrekonstruktion, Universitätsklinik für Chirurgie, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich.

Klinische Abteilung für Plastische und Rekonstruktive Chirurgie, Universitätsklinik für Chirurgie, Medizinische Universität Wien, Wien, Österreich.

出版信息

Orthopade. 2021 Jan;50(1):14-23. doi: 10.1007/s00132-020-04032-1.

DOI:10.1007/s00132-020-04032-1
PMID:33231741
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7815562/
Abstract

BACKGROUND

After limb loss, it is the surgeon's task to provide the patient with a pain-free and resilient residual limb. Particularly in the upper extremity, there is an additional functional aspect, as appropriate muscle signals are needed to control myoelectric prostheses. Surgical management of peripheral nerves within the residual limb plays a central role both in terms of pain treatment as well as functional human-machine interfacing.

OBJECTIVES

The presentation of current surgical procedures for dealing with peripheral nerves after limb amputation.

MATERIAL AND METHODS

A literature search is carried out regarding the surgical prophylaxis and therapy of neuroma and phantom limb pain, as well as techniques to improve the functional interface between residual limb and prosthesis. Practical recommendations are formulated based on relevant literature, as well as the experiences of the authors.

RESULTS AND CONCLUSIONS

There is a large number of different surgical techniques, particularly for the management of painful neuromas. Of the conventional methods, intramuscular implantation of the terminal nerves is commonly used with good results. Newer techniques such as targeted muscle reinnervation (TMR) and the regenerative peripheral nerve interface (RPNI) aim for the first time to provide functional end organs to the nerve even after amputation. In addition to the improved control of myoelectric prostheses, these methods further show excellent results for treatment and prevention of neuroma and phantom limb pain.

摘要

背景

肢体缺失后,外科医生的任务是为患者提供无痛且有弹性的残肢。特别是在上肢,还有一个额外的功能方面,因为需要适当的肌肉信号来控制肌电假肢。残肢内周围神经的外科处理在疼痛治疗以及功能性人机接口方面都起着核心作用。

目的

介绍肢体截肢后处理周围神经的当前外科手术方法。

材料与方法

对神经瘤和幻肢痛的外科预防和治疗以及改善残肢与假肢之间功能接口的技术进行文献检索。根据相关文献以及作者的经验制定实用建议。

结果与结论

有大量不同的外科技术,特别是用于处理疼痛性神经瘤。在传统方法中,终末神经肌肉内植入术常用且效果良好。诸如靶向肌肉再支配(TMR)和再生周围神经接口(RPNI)等新技术首次旨在即使在截肢后也为神经提供功能性终末器官。除了改善肌电假肢的控制外,这些方法在治疗和预防神经瘤及幻肢痛方面也显示出优异的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/7a755a4f1c9f/132_2020_4032_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/6be22a6d213b/132_2020_4032_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/0c3235f412e2/132_2020_4032_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/7544597fc69b/132_2020_4032_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/7a755a4f1c9f/132_2020_4032_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/6be22a6d213b/132_2020_4032_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/0c3235f412e2/132_2020_4032_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/7544597fc69b/132_2020_4032_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035f/7815562/7a755a4f1c9f/132_2020_4032_Fig4_HTML.jpg

相似文献

1
[Surgical management of peripheral nerves after extremity loss].[肢体缺失后周围神经的外科处理]
Orthopade. 2021 Jan;50(1):14-23. doi: 10.1007/s00132-020-04032-1.
2
Targeted muscle reinnervation: a novel approach to postamputation neuroma pain.靶向肌肉神经再支配:一种治疗截肢后神经瘤疼痛的新方法。
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Eur J Orthop Surg Traumatol. 2024 Oct;34(7):3717-3725. doi: 10.1007/s00590-023-03736-2. Epub 2023 Oct 9.
4
Peripheral Nerve Management in Extremity Amputations.四肢截肢中的周围神经处理
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Targeted Muscle Reinnervation Technique in Below-Knee Amputation.靶向肌肉神经再支配技术在膝下截肢中的应用。
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Utilization of Techniques for Upper Extremity Amputation Neuroma Treatment and Prevention.上肢截肢神经瘤治疗和预防技术的应用。
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Prophylactic Regenerative Peripheral Nerve Interfaces to Prevent Postamputation Pain.预防性再生周围神经界面预防截肢后疼痛。
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PM R. 2023 Nov;15(11):1457-1465. doi: 10.1002/pmrj.12972. Epub 2023 May 28.

引用本文的文献

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[Fillet flap transfer as alternative to conventional lower limb amputation].[鱼片皮瓣转移术作为传统下肢截肢术的替代方法]
Unfallchirurgie (Heidelb). 2024 Sep;127(9):651-659. doi: 10.1007/s00113-024-01460-y. Epub 2024 Jul 10.
2
Feasibility of Magnetic Resonance-Guided High-Intensity-Focused Ultrasound (MRgHIFU) Ablation of Stump Neuromas for the Relief of Chronic Postamputation Neuropathic Pain.磁共振引导高强度聚焦超声(MRgHIFU)消融残端神经瘤治疗慢性截肢后神经病理性疼痛的可行性。
J Ultrasound Med. 2022 Dec;41(12):3119-3124. doi: 10.1002/jum.16026. Epub 2022 May 28.
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Trigeminal Traumatic Neuroma: a Comprehensive Review of the Literature Based On a Rare Case.

本文引用的文献

1
Regenerative Peripheral Nerve Interfaces for the Management of Symptomatic Hand and Digital Neuromas.用于治疗症状性手部和指神经瘤的再生周围神经接口
Plast Reconstr Surg Glob Open. 2020 Jun 4;8(6):e2792. doi: 10.1097/GOX.0000000000002792. eCollection 2020 Jun.
2
In musculus, veritas? Nerve "in muscle" versus targeted muscle reinnervation versus regenerative peripheral nerve interface: Historical review.肌肉中存在真理?“肌肉内”神经与靶向肌肉再支配与再生性周围神经接口:历史回顾
Microsurgery. 2020 May;40(4):516-522. doi: 10.1002/micr.30575. Epub 2020 Mar 17.
3
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat.
三叉神经创伤性神经瘤:基于罕见病例的文献综合回顾。
Curr Pain Headache Rep. 2022 Mar;26(3):219-233. doi: 10.1007/s11916-022-01018-w. Epub 2022 Feb 4.
成年大鼠复合再生周围神经接口(C-RPNI)的制备
J Vis Exp. 2020 Feb 25(156). doi: 10.3791/60841.
4
A regenerative peripheral nerve interface allows real-time control of an artificial hand in upper limb amputees.再生周围神经接口允许上肢截肢者实时控制假手。
Sci Transl Med. 2020 Mar 4;12(533). doi: 10.1126/scitranslmed.aay2857.
5
Outcomes, Challenges, and Pitfalls after Targeted Muscle Reinnervation in High-Level Amputees: Is It Worth the Effort?高位截肢患者接受靶向肌肉神经再支配后的结果、挑战和陷阱:值得付出努力吗?
Plast Reconstr Surg. 2019 Dec;144(6):1037e-1043e. doi: 10.1097/PRS.0000000000006277.
6
Novel Use of Targeted Muscle Reinnervation in the Hand for Treatment of Recurrent Symptomatic Neuromas Following Digit Amputations.靶向肌肉再支配技术在手部治疗指截肢后复发性症状性神经瘤中的新应用。
Plast Reconstr Surg Glob Open. 2019 Aug 8;7(8):e2376. doi: 10.1097/GOX.0000000000002376. eCollection 2019 Aug.
7
Prophylactic Regenerative Peripheral Nerve Interfaces to Prevent Postamputation Pain.预防性再生周围神经界面预防截肢后疼痛。
Plast Reconstr Surg. 2019 Sep;144(3):421e-430e. doi: 10.1097/PRS.0000000000005922.
8
Imaging of Peripheral Nerves of the Upper Extremity.上肢周围神经成像
Radiol Clin North Am. 2019 Sep;57(5):1063-1071. doi: 10.1016/j.rcl.2019.04.001. Epub 2019 Jun 5.
9
Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation.在大肢体截肢时,通过靶向肌肉神经再支配对幻肢和残肢痛进行预防性治疗。
J Am Coll Surg. 2019 Mar;228(3):217-226. doi: 10.1016/j.jamcollsurg.2018.12.015. Epub 2019 Jan 8.
10
Peripheral nerve transfers change target muscle structure and function.周围神经转移改变靶肌肉的结构和功能。
Sci Adv. 2019 Jan 2;5(1):eaau2956. doi: 10.1126/sciadv.aau2956. eCollection 2019 Jan.