Gaw Christopher E, Osterhoudt Kevin C
Resident Physician, Division of General Pediatrics.
Professor of Pediatrics and Medical Director of Poison Control Center, Division of Emergency Medicine.
Pediatr Emerg Care. 2019 Oct;35(10):722-730. doi: 10.1097/PEC.0000000000001946.
Ethanol intoxication of infants and young children can be a challenging diagnosis in the pediatric emergency department, and features of the poisoning may differ in comparison with adolescents. The sources of ethanol exposures in this age are varied and include unintentional, malicious, and iatrogenic etiologies. Young children exposed to ethanol often present with mixed clinical signs and symptoms that may not fit the traditional ethanol or sedative-hypnotic toxidrome. Pediatric ethanol intoxications are often managed supportively, and recovery is usually rapid. The purpose of this review is to describe the sources of ethanol poisoning among children 6 years and younger, highlight presenting symptoms and pharmacokinetic considerations unique to this age group, and review management strategies. In addition, published cases of ethanol poisoning due to ingestion among young infants are compiled for presentation.
婴幼儿乙醇中毒在儿科急诊科可能是一个具有挑战性的诊断，与青少年相比，中毒的特征可能有所不同。这个年龄段乙醇暴露的来源多种多样，包括无意、恶意和医源性病因。接触乙醇的幼儿通常表现出混合的临床体征和症状，可能不符合传统的乙醇或镇静催眠药中毒综合征。儿科乙醇中毒通常采用支持性治疗，恢复通常很快。本综述的目的是描述6岁及以下儿童乙醇中毒的来源，强调该年龄组特有的症状表现和药代动力学考虑因素，并回顾管理策略。此外，还汇编了已发表的幼儿因摄入乙醇中毒的病例以供展示。
