Fong Hiu-Fai, Muller Allison A
From the *Department of Pediatrics, The Children's Hospital of Philadelphia; Robert Wood Johnson Foundation Clinical Scholars Program and Leonard Davis Institute of Health Economics, The Perelman School of Medicine at the University of Pennsylvania; and †The Institute for Continuing Healthcare Education and the University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA.
Pediatr Emerg Care. 2014 Feb;30(2):111-3. doi: 10.1097/PEC.0000000000000068.
Ethanol exposure can affect all pediatric age groups but occurs most commonly in ambulatory children and adolescents. Infants are less likely to ingest ethanol because they have limited ability to explore their environments. However, ethanol exposures in infants can occur. We report the case of a 29-day-old (3.5 kg) baby girl who presented with a blood alcohol level of 301 mg/dL after ingesting formula that had been prepared with gin. To our knowledge, she is the youngest reported child with such an elevated ethanol level in the medical literature. Despite her markedly elevated blood alcohol level, she had an unexpectedly mild clinical course, exhibiting subtle neurologic symptoms but no hypothermia, hypoglycemia, or cardiorespiratory impairment. This case demonstrates that the ethanol-exposed infant may lack typical or clear symptoms of acute intoxication. Therefore, the clinician must have a low threshold for pursuing blood alcohol testing in infants and young children with altered mental status. A prompt diagnosis of ethanol exposure is important for ensuring the health and safety of the child.
乙醇暴露可影响所有儿童年龄组，但最常见于门诊儿童和青少年。婴儿摄入乙醇的可能性较小，因为他们探索环境的能力有限。然而，婴儿也可能发生乙醇暴露。我们报告一例29日龄（3.5千克）女婴，她在摄入用杜松子酒配制的配方奶后，血液酒精水平达到301毫克/分升。据我们所知，她是医学文献中报道的血液酒精水平如此之高的最年幼患儿。尽管她的血液酒精水平显著升高，但她的临床过程出人意料地轻微，仅表现出轻微的神经症状，没有体温过低、低血糖或心肺功能损害。该病例表明，暴露于乙醇的婴儿可能缺乏典型或明显的急性中毒症状。因此，临床医生对于对精神状态改变的婴幼儿进行血液酒精检测应保持较低的阈值。及时诊断乙醇暴露对于确保儿童的健康和安全至关重要。
