Deskur Anna, Zawada Iwona, Błogowski Wojciech, Starzyńska Teresa
Department of Gastroenterology, Pomeranian Medical University, Szczecin.
Department of Internal Medicine, University of Zielona Góra, Zielona Góra, Poland.
Medicine (Baltimore). 2019 Oct;98(41):e17428. doi: 10.1097/MD.0000000000017428.
Cerebral venous sinus thrombosis (CVST) represents one of the most alarming forms of hemostatic abnormalities that may occur in patients with inflammatory bowel diseases (IBDs).
Here we report a case of a 25-year-old male with ulcerative colitis, who developed such thromboembolic complication during flare of the disease. CVST in our patient was clinically manifested by headache and nausea.
Angio-magnetic resonance imaging scan of the head revealed segments of contrast filling defects/absence indicating right dural venous sinus thrombosis of the transverse sinus.
Immediate treatment with low-molecular-weight heparin has been introduced and led to full remission of symptoms and total recanalization of the thrombotic cerebral regions.
Currently (over 2 years after diagnosis) the patient is in remission of the disease, and no further thromboembolic complications have been observed.
Our case study highlights the clinical difficulties and challenges associated with diagnosis and treatment of CVST, as well as presents the current state of knowledge about this complication among patients with IBDs. Physicians taking care of IBD patients should be aware of this alarming hemostatic abnormality.
脑静脉窦血栓形成（CVST）是炎症性肠病（IBD）患者可能出现的最令人担忧的止血异常形式之一。
我们在此报告一例25岁患有溃疡性结肠炎的男性患者，在疾病发作期间出现了这种血栓栓塞并发症。我们患者的CVST临床表现为头痛和恶心。
头部血管磁共振成像扫描显示造影剂充盈缺损/缺失区域，提示右侧横窦硬脑膜静脉窦血栓形成。
立即采用低分子量肝素进行治疗，症状完全缓解，血栓形成的脑区完全再通。
目前（诊断后2年多）患者疾病处于缓解期，未观察到进一步的血栓栓塞并发症。
我们的病例研究突出了与CVST诊断和治疗相关的临床困难与挑战，同时展示了IBD患者中关于这种并发症的当前知识状况。照料IBD患者的医生应意识到这种令人担忧的止血异常情况。
