Department of Biochemistry, Liaquat University of Medical and Health Sciences, Jamshoro, Sindh, Pakistan.
Curr Hypertens Rev. 2020;16(3):216-222. doi: 10.2174/1573402115666191009120640.
Preeclampsia is multi-systemic hypertensive pregnancy disorder accompanied by proteinuria.
To determine the frequency of different presentations of preeclampsia in tertiary care hospital and find out its risk factors.
The present study was hospital-based cross-sectional study and conducted from 1st August 2015 to 31st July 2016 in Gynaecology and Obstetrics Department, Liaquat University of Medical and Health Sciences (LUMHS), Hyderabad after ethical approval. A total of 112 pre-eclamptic women were enrolled during the study period by non-probability consecutive sampling. Patients were divided on the basis of their presentations into mild preeclampsia, severe preeclampsia, antepartum eclampsia, intrapartum eclampsia, HELLP syndrome, postpartum preeclampsia, postpartum eclampsia and atypical preeclampsia/eclampsia. All the sociodemographic factors and clinical variables were noted. Frequency and percentage were calculated for categorical variable and mean/standard deviation (SD) for continuous variables.
Of the 112 preeclamptic women, 54.5% were admitted with antepartum eclampsia, 12.5% with severe preeclampsia, 8.9% with atypical preeclampsia/eclampsia, 8% with mild preeclampsia, 8% with postpartum eclampsia, 3.6% with HELLP syndrome, 2.7% with intrapartum eclampsia and 1.8% with postpartum preeclampsia. Overall, majority of the patients were primigravida (57%), had gestational age >34 weeks at presentation (58.9%) and < 7 antenatal visits (88.3%) during their pregnancy. Overall 17.8% had previous bad obstetrical events, 11.6% had previous history of preeclampsia and 64.3% had consanguineous marriages.
Different presentations of preeclampsia may help obstetricians to rule out high- risk pregnancies and provide antenatal care to patients earlier to prevent complications to both mother and fetus.
子痫前期是一种多系统高血压妊娠疾病,伴有蛋白尿。
确定三级保健医院子痫前期的不同表现频率,并找出其危险因素。
本研究为医院为基础的横断面研究,于 2015 年 8 月 1 日至 2016 年 7 月 31 日在海得拉巴的拉奎特大学医学和健康科学学院(LUMHS)妇产科进行,经过伦理批准。在研究期间,通过非概率连续抽样共纳入 112 例子痫前期患者。根据表现将患者分为轻度子痫前期、重度子痫前期、产前子痫、产时子痫、HELLP 综合征、产后子痫、产后子痫和非典型子痫前期/子痫。记录所有社会人口统计学因素和临床变量。对分类变量计算频率和百分比,对连续变量计算均值/标准差(SD)。
在 112 例子痫前期患者中,54.5%为产前子痫入院,12.5%为重度子痫前期,8.9%为非典型子痫前期/子痫,8%为轻度子痫前期,8%为产后子痫,3.6%为 HELLP 综合征,2.7%为产时子痫,1.8%为产后子痫。总体而言,大多数患者为初产妇(57%),在就诊时的孕龄>34 周(58.9%),妊娠期间的产前检查<7 次(88.3%)。总体上,17.8%有不良产科病史,11.6%有子痫前期病史,64.3%有近亲结婚。
子痫前期的不同表现形式可以帮助产科医生排除高危妊娠,并为患者提供更早的产前护理,以预防母婴并发症。