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用于治疗Pierre Robin序列患儿阻塞性睡眠呼吸暂停的正畸板:香港的经验与方案

Orthodontic plate for management of obstructive sleep apnoea in infants with Pierre Robin sequence: experience and protocol in Hong Kong.

作者信息

Ho Angus Ch, Wong Ricky Wk, Cheung Tania, Ng Daniel K, Siu K K, Fung S C

机构信息

Department of Dentistry and Maxillofacial Surgery, United Christian Hospital, Hong Kong.

Private practice, Hong Kong.

出版信息

J Orthod. 2019 Dec;46(4):367-373. doi: 10.1177/1465312519880557. Epub 2019 Oct 10.

Abstract

OBJECTIVE

To present the application of the pre-epiglottic baton plate (PEBP) in infants with Pierre Robin sequence (PRS) in the Southern Chinese population (Hong Kong) and to present the diagnosis and management protocol of these infants in our centre.

DESIGN

Retrospective case series of three patients with PRS.

SETTING

Neonatal Intensive Care Unit in Kwong Wah Hospital and Craniofacial Orthodontic Centre in United Christian Hospital, Hong Kong.

PARTICIPANTS

Three new-born infants (two girls, one boy) with PRS and upper airway obstruction due to glossoptosis.

METHODS

A protocol for the diagnosis and management of these infants in the Southern Chinese population (Hong Kong) was presented. The three patients received nasal high-flow oxygen and/or continuous positive airway pressure (CPAP) as first-line respiratory support, followed by PEBP for 3-5 months. A two-stage approach was undertaken to ensure accurate positioning of the PEBP.

RESULTS

All three infants had improvement in clinical signs, symptoms and polysomnography upon discharge. PEBP and other respiratory aids were weaned off at 3-6 months.

CONCLUSIONS

The PEBP, combined with other respiratory support, is a useful modality in the treatment of obstructive sleep apnoea in infants with PRS.

摘要

目的

介绍会厌前棒状板(PEBP)在华南地区(香港)患有皮埃尔·罗宾序列征(PRS)的婴儿中的应用,并展示本中心对这些婴儿的诊断和管理方案。

设计

对3例PRS患者的回顾性病例系列研究。

地点

香港广华医院新生儿重症监护病房和联合医院颅面正畸中心。

参与者

3例患有PRS且因舌后坠导致上气道梗阻的新生儿(2名女孩,1名男孩)。

方法

介绍了针对华南地区(香港)这些婴儿的诊断和管理方案。3例患者接受鼻高流量给氧和/或持续气道正压通气(CPAP)作为一线呼吸支持,随后使用PEBP 3至5个月。采用两阶段方法以确保PEBP的准确定位。

结果

所有3例婴儿出院时临床体征、症状及多导睡眠图均有改善。PEBP及其他呼吸辅助设备在3至6个月时停用。

结论

PEBP联合其他呼吸支持手段,是治疗患有PRS的婴儿阻塞性睡眠呼吸暂停的有效方式。

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