Ramirez-Yanez German O, Scott James E
Aurora Kids Dentistry, Aurora, Canada, Phone: +1 647 963 5716, e-mail:
Department of Oral Biology, College of Dentistry, University of Manitoba, Winnipeg, Canada.
J Contemp Dent Pract. 2019 Jul 1;20(7):768-772.
This study aimed to categorize the constituent tissues of the mandibular condylar cartilage of elderly individuals.
Thirty-three mandibular condyles were collected from 20 human cadavers of individuals between 40 years and 103 years old. Samples were stained with Masson's trichrome and Herovici's stains and, examined under a light microscope.
All samples showed tissues that were categorized as fibrous and hyaline cartilage in the mandibular condylar cartilage. A thick fibrous cartilage layer was differentiated on the top of a thinner hyaline cartilage in all of the examined samples. Undifferentiated cells, as well as mature and hypertrophic chondroblasts, were observed in the layer identified as hyaline cartilage, even though they were not in an organized manner.
The observations from this study confirm that both fibrocartilage and hyaline cartilage are still present in the mandibular condylar cartilage of elderly individuals.
The results from this study infer that the mandibular condylar cartilage could be still able to respond to stimulus in adults. In that context, the results of the present study set the basis for future studies aiming to elucidate the biological activity and the remodeling potential of the tissues at the mandibular condyle in adults.
本研究旨在对老年人下颌髁突软骨的组成组织进行分类。
从20具年龄在40岁至103岁之间的人类尸体上收集了33个下颌髁突。样本用Masson三色染色法和赫罗维奇染色法染色，并在光学显微镜下检查。
所有样本在下颌髁突软骨中均显示出可分为纤维软骨和透明软骨的组织。在所有检查样本中，较薄的透明软骨顶部有一层厚厚的纤维软骨层。在被鉴定为透明软骨的层中观察到了未分化细胞以及成熟和肥大的软骨细胞，尽管它们并非呈有组织的方式排列。
本研究的观察结果证实，纤维软骨和透明软骨在老年人的下颌髁突软骨中仍然存在。
本研究结果推断，下颌髁突软骨在成年人中仍可能能够对刺激做出反应。在此背景下，本研究结果为未来旨在阐明成年人下颌髁突组织的生物活性和重塑潜力的研究奠定了基础。
