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细胞分辨率人体图谱:NIH 人类生物分子图谱计划。

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program.

出版信息

Nature. 2019 Oct;574(7777):187-192. doi: 10.1038/s41586-019-1629-x. Epub 2019 Oct 9.

Abstract

Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to develop a widely accessible framework for comprehensively mapping the human body at single-cell resolution by supporting technology development, data acquisition, and detailed spatial mapping. HuBMAP will integrate its efforts with other funding agencies, programs, consortia, and the biomedical research community at large towards the shared vision of a comprehensive, accessible three-dimensional molecular and cellular atlas of the human body, in health and under various disease conditions.

摘要

变革性技术正在以前所未有的空间和分子分辨率构建组织的三维图谱。在未来七年,NIH 共同基金人类生物分子图谱计划(HuBMAP)旨在通过支持技术开发、数据采集和详细的空间图谱绘制,开发一个广泛可访问的框架,以单细胞分辨率全面绘制人体图谱。HuBMAP 将其努力与其他资助机构、计划、联盟以及整个生物医学研究界整合在一起,朝着一个全面、可访问的人类身体三维分子和细胞图谱的共同愿景努力,无论在健康状态还是各种疾病条件下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1362/6800388/bcd6caf02a52/41586_2019_1629_Fig1_HTML.jpg

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