Department of Medicine, Washington University School of Medicine, St Louis, MO, USA.
Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.
Nat Cell Biol. 2023 Aug;25(8):1089-1100. doi: 10.1038/s41556-023-01194-w. Epub 2023 Jul 19.
The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale spatial atlas of the healthy human body at single-cell resolution by applying advanced technologies and disseminating resources to the community. As the HuBMAP moves past its first phase, creating ontologies, protocols and pipelines, this Perspective introduces the production phase: the generation of reference spatial maps of functional tissue units across many organs from diverse populations and the creation of mapping tools and infrastructure to advance biomedical research.
人类生物分子图谱计划（HuBMAP）旨在通过应用先进技术并向社区传播资源，以单细胞分辨率创建健康人体的多尺度空间图谱。随着 HuBMAP 进入其第一阶段（创建本体、协议和管道）之后，本观点介绍了其生产阶段：从多个器官的不同人群中生成功能组织单位的参考空间图谱，并创建映射工具和基础设施以推进生物医学研究。
