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克氏锥虫:寄生骨骼肌纤维的组织化学特征

Trypanosoma cruzi: histochemical characterization of parasitized skeletal muscle fibers.

作者信息

Teixeira M L, Dvorak J A

出版信息

J Protozool. 1985 May;32(2):339-41. doi: 10.1111/j.1550-7408.1985.tb03062.x.

DOI:10.1111/j.1550-7408.1985.tb03062.x
PMID:3159887
Abstract

C57B1/6 mice were infected with Brasil strain Trypanosoma cruzi trypomastigotes. The leg muscles of the mice were serial-sectioned with a cryostat, and individual fibers were classified histochemically as type I or type II on the basis of succinic dehydrogenase or adenosine triphosphatase activity. Although markedly more type II fibers were present in the leg muscles, the percentage of infected type I fibers was nearly five-fold higher than type II. This is the first demonstration of a preferential in vivo distribution of T. cruzi in muscle fibers based upon muscle type.

摘要

将C57B1/6小鼠感染巴西株克氏锥虫的锥鞭毛体。用低温恒温器对小鼠的腿部肌肉进行连续切片,并根据琥珀酸脱氢酶或三磷酸腺苷酶活性,通过组织化学方法将单个肌纤维分为I型或II型。尽管腿部肌肉中明显存在更多的II型肌纤维,但I型感染肌纤维的百分比几乎是II型的五倍。这是首次基于肌肉类型对克氏锥虫在肌纤维中的体内优先分布进行的证明。

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Trypanosoma cruzi: histochemical characterization of parasitized skeletal muscle fibers.克氏锥虫:寄生骨骼肌纤维的组织化学特征
J Protozool. 1985 May;32(2):339-41. doi: 10.1111/j.1550-7408.1985.tb03062.x.
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[Trypanosoma cruzi: induction of changes in the peripheral nervous system in different strains of mice].[克氏锥虫:不同品系小鼠外周神经系统变化的诱导]
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引用本文的文献

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Selectivity of alterations in skeletal fibers in chronic Chagas' disease of the mouse.小鼠慢性恰加斯病骨骼肌纤维变化的选择性
Experientia. 1988 Jan 15;44(1):14-6. doi: 10.1007/BF01960225.