CNRS, LNC, Aix-Marseille Université, Marseille, France.
CNRS, LPL, Aix-Marseille Université, Aix-en-Provence, France.
Ann N Y Acad Sci. 2020 Apr;1465(1):132-145. doi: 10.1111/nyas.14252. Epub 2019 Oct 10.
A growing number of studies postulate the use of music to improve motor control in patients with Parkinson's disease (PD). The effects of music are greatly variable from one individual to the other and do not always reach the expected benefits. This study aimed to optimize the use of music in the management of movement disorders inherent to PD in a handwriting task. We developed and tested musical sonification (MS), a method that transforms in real-time kinematic variables into music. Twelve patients with PD, on medication, and 12 healthy controls were recruited in a pretest/training/posttest design experiment. Three training sessions were compared, for which participants were asked to produce graphomotor exercises: one session with music (unrelated to handwriting), one with MS (controlled by handwriting), and one in silence. Results showed that the performance in training was better under MS than under silence or background music, for both groups. After training, the benefits of MS were still present for both groups, with a higher effect for PD patients than for control group. Our results provide a proof of concept to consider MS as a relevant auditory guidance strategy for movement rehabilitation in patients with PD.
越来越多的研究假设使用音乐来改善帕金森病（PD）患者的运动控制。音乐的效果因人而异，差异很大，并不总是能达到预期的效果。本研究旨在通过手写任务优化音乐在 PD 固有运动障碍管理中的应用。我们开发并测试了音乐发声（MS），这是一种将运动学变量实时转换为音乐的方法。12 名正在服用药物的 PD 患者和 12 名健康对照者参加了预测试/训练/后测试设计实验。比较了三个训练阶段，要求参与者进行图运动练习：一个有音乐（与手写无关）的阶段，一个有 MS（由手写控制）的阶段，一个无声的阶段。结果表明，两组在 MS 下的训练表现均优于无声或背景音乐。经过训练，MS 的益处对两组都仍然存在，对 PD 患者的效果高于对照组。我们的结果提供了一个概念验证，认为 MS 是一种用于 PD 患者运动康复的相关听觉指导策略。
