Morsches B, Benes P, Hopp J R
Z Hautkr. 1985 May 15;60(10):808, 813-4, 817-8.
In 30 female patients suffering from acne vulgaris and 32 female controls, we determined the plasma levels of androstenedione, testosterone and dihydrotestosterone. The average rates of all three androgens were significantly increased in acne. But only the dihydrotestosterone rate showed a clear separation from the individual values of the two collectives. These findings suggest increased synthesis of dihydrotestosterone within the skin of patients with acne vulgaris.
在30名寻常痤疮女性患者和32名女性对照者中,我们测定了血浆雄烯二酮、睾酮和双氢睾酮水平。痤疮患者中所有这三种雄激素的平均水平均显著升高。但只有双氢睾酮水平与两个群体的个体值有明显差异。这些发现提示寻常痤疮患者皮肤内双氢睾酮合成增加。