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心血管麻醉医师学会关于心脏外科手术患者围术期出血及止血管理的临床实践改进建议。

Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Advisory for Management of Perioperative Bleeding and Hemostasis in Cardiac Surgery Patients.

机构信息

University of Virginia Health System, Charlottesville, VA.

St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

出版信息

J Cardiothorac Vasc Anesth. 2019 Nov;33(11):2887-2899. doi: 10.1053/j.jvca.2019.04.003. Epub 2019 Apr 19.

Abstract

Bleeding after cardiac surgery is a common and serious complication leading to transfusion of multiple blood products and resulting in increased morbidity and mortality. Despite the publication of numerous guidelines and consensus statements for patient blood management in cardiac surgery, research has revealed that adherence to these guidelines is poor, and as a result, a significant variability in patient transfusion practices among practitioners still remains. In addition, although utilization of point of care coagulation monitors and the use of novel therapeutic strategies for perioperative hemostasis, such as the use of coagulation factor concentrates, has increased significantly over the last decade, they are still not widely available in every institution. Therefore, despite continuous efforts, blood transfusion in cardiac surgery has declined only modestly over the last decade, remaining at 50% or greater in high-risk patients. Given these limitations and in response to new regulatory and legislature requirements, the Society of Cardiovascular Anesthesiologists has formed the Blood Conservation in Cardiac Surgery Working Group in order to organize, summarize, and disseminate the available best-practice knowledge in patient blood management in cardiac surgery. The current publication includes the summary statements and algorithms designed by the working group, after collection and review of the existing guidelines, consensus statements, and recommendations for patient blood management practices in cardiac surgery patients. The overall goal is creating a dynamic resource of easily accessible educational material that will help to increase and improve compliance with the existing evidence-based best practices of patient blood management by cardiac surgery care teams.

摘要

心脏手术后出血是一种常见且严重的并发症,可导致输注多种血液制品,并导致发病率和死亡率增加。尽管已经发布了许多关于心脏手术患者血液管理的指南和共识声明,但研究表明,这些指南的遵循情况很差,因此,医生之间的患者输血实践仍然存在很大差异。此外,尽管近十年来,即时凝血监测器的使用和围手术期止血的新型治疗策略(如凝血因子浓缩物的使用)的使用显著增加,但它们在每个医疗机构中仍然没有广泛应用。因此,尽管不断努力,心脏手术中的输血在过去十年中仅略有下降,高危患者的输血仍占 50%或以上。鉴于这些局限性,并为了响应新的监管和立法要求,心血管麻醉医师学会成立了心脏手术血液保护工作组,以便组织、总结和传播心脏手术患者血液管理方面的最佳实践知识。本出版物包括工作组收集和审查现有的指南、共识声明和心脏手术患者血液管理实践建议后制定的总结陈述和算法。总体目标是创建一个易于访问的教育材料的动态资源,以帮助增加和提高心脏外科护理团队对现有基于证据的最佳患者血液管理实践的遵守。

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