Basora M, Fita G, Panigua P, Litvan H, Fló A, Reverter J C
Servicio de Anestesiología y Reanimación, Hospital Clínic, Barcelona.
Rev Esp Anestesiol Reanim. 2010 Jan;57(1):3-10. doi: 10.1016/s0034-9356(10)70156-0.
To determine practices related to control of perioperative hemostasis and transfusion in patients undergoing cardiac surgery in Spain, including the extent to which protocols are being used.
A questionnaire was created to collect information from physicians in anesthesiology and postoperative recovery care between July 1 and September 20, 2007. The physicians were asked about practice in the 12 months prior to the survey.
Thirty-four hospitals responded. Seventy percent reported that they did not have protocols or guidelines for the control of hemostasis during cardiac surgery. Forty-four percent did not have information on the proportion of patients who received transfusions; 47% gave transfusions to 75% of patients. The standard preoperative tests were platelet counts, activated partial thromboplastin time, and prothrombin time. Acetylsalicylic acid and clopidogrel were suspended before surgery at 15 (44%) and 25 (73%) hospitals, respectively. In cases of resistance to heparin, additional doses of the drug were injected, in combination with plasma or antithrombin in 29% and 12% of the hospitals, respectively. In the intensive postoperative recovery care unit, only 1 hospital used thromboelastography. Only 1 other hospital used a platelet function analyzer.
Hemostasis, perioperative coagulation, and criteria for transfusion vary widely among the hospitals surveyed. Few guidelines are available and they are not often being followed. A high percentage of patients receive transfusions, although not all hospitals can cite a figure. New technology has not been widely applied.
确定西班牙心脏手术患者围手术期止血和输血控制的相关做法,包括方案的使用程度。
设计了一份问卷,以收集2007年7月1日至9月20日期间麻醉和术后恢复护理方面医生的信息。询问医生关于调查前12个月的做法。
34家医院做出回应。70%的医院报告称,他们没有心脏手术期间止血控制的方案或指南。44%的医院没有患者输血比例的信息;47%的医院给75%的患者输了血。术前标准检查为血小板计数、活化部分凝血活酶时间和凝血酶原时间。分别有15家(44%)和25家(73%)医院在手术前停用了阿司匹林和氯吡格雷。在肝素抵抗的情况下,分别有29%和12%的医院注射额外剂量的药物,并联合使用血浆或抗凝血酶。在术后重症恢复护理病房,只有1家医院使用血栓弹力图。只有另1家医院使用血小板功能分析仪。
在所调查的医院中,止血、围手术期凝血和输血标准差异很大。可用的指南很少,且不常被遵循。尽管并非所有医院都能给出具体数字,但仍有很高比例的患者接受输血。新技术尚未得到广泛应用。