Nuclear Medicine Department, Royal United Hospitals Bath, Combe Park, Avon, United Kingdom; and.
Auckland District Health Board, Auckland City Hospital, Grafton, Auckland, New Zealand.
J Nucl Med Technol. 2020 Mar;48(1):46-50. doi: 10.2967/jnmt.119.233577. Epub 2019 Oct 11.
Bone scintigraphy is one of the most common nuclear medicine tests. Previous work investigated the effectiveness of an asymmetric window (ASW) for planar bone scintigraphy using simulation and phantom data. Phantom studies concluded that the ASW improved both the resolution and the contrast-to-noise ratio when imaging objects with high scatter. The aim of this study was to confirm this improvement increased image quality in patients. This study also investigated whether the differences between a symmetric window (SW) and an ASW depended on body mass index. Fifty-eight patients had 2 scans: a standard scan using an SW of 140 keV ± 10% and a scan using an ASW of 140 keV + 10% and - 7.5%. Three readers independently compared the 2 image sets and scored them using a 5-score scale (ranging from 1 = ASW better [clinically important] to 5 = SW better [clinically important]). Scores from all radiologists were pooled and analyzed statistically. A value of less than 0.05 was considered statistically significant. In 93 cases (53%), the readers scored the ASW images better than the SW images. In 5 cases (3%), the ASW images were preferred, with the difference considered clinically important; there were no cases in which the SW was similarly preferred. For the sign test, we determined whether the total of 93 scores of 1 or 2 (ASW preferred) was significantly different from the 15 scores of 4 or 5 (SW preferred). The value was less than 0.00001, demonstrating that the difference was significant. In patients undergoing bone scintigraphy, ASW provided an improvement in image quality that in some cases was judged clinically important.
骨闪烁成像术是最常用的核医学检查之一。先前的研究通过模拟和体模数据探讨了非对称窗（ASW）在平面骨闪烁成像中的有效性。体模研究的结论是，当对高散射物体成像时，ASW 可提高分辨率和对比噪声比。本研究旨在证实这种改善可提高患者的图像质量。本研究还探讨了 ASW 和 SW 之间的差异是否取决于体重指数。58 例患者进行了 2 次扫描：使用 140keV±10%SW 的标准扫描和使用 140keV+10%和-7.5%ASW 的扫描。3 位阅片者独立比较了这 2 组图像，并使用 5 分制评分（1 分表示 ASW 更好[具有临床意义]，5 分表示 SW 更好[具有临床意义]）对其进行评分。所有放射科医生的评分均被汇总并进行统计学分析。小于 0.05 的 值被认为具有统计学意义。在 93 例（53%）中，读者认为 ASW 图像优于 SW 图像。在 5 例（3%）中，ASW 图像更受青睐，且这种差异被认为具有临床意义；SW 图像更受青睐的情况无一例。对于符号检验，我们确定 93 个 1 或 2 分（ASW 更优）的总和与 15 个 4 或 5 分（SW 更优）是否存在显著差异。 值小于 0.00001，表明差异具有统计学意义。在进行骨闪烁成像术的患者中，ASW 可提高图像质量，在某些情况下，这种改善被认为具有临床意义。
