Zhu A Q, Zheng Y M, Qin Y, Liu S S, Cui J Z, Li Z L, Li S, Feng L Z, Li Z J
Division of Infectious Disease, Key Laboratory of Infectious Disease Surveillance and Ear-warning, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Oct 6;53(10):1043-1048. doi: 10.3760/cma.j.issn.0253-9624.2019.10.017.
To understand the status of studies about influenza economic burden in mainland China and summarize their major results. The words of influenza, flu, cost, economic, burden, effectiveness, benefit, utility, China, and Chinese, were used as search keywords. Journal papers published during 2000-2018 were searched from Chinese electronic databases (CNKI and Wanfang) and English electronic databases (PubMed, Web of science, EconLit and Cochrane Library). The language of literature was restricted to Chinese and English. A total of 23 effective documents were included, and the descriptive characteristics, research indexes and methods included in the literature were analyzed. The monetary unit used in this review is Chinese Yuan (CNY). The 23 study sites were mainly in the relatively developed and populous regions. The total cost per capita of laboratory-confirmed influenza,of all age-group was reported in 6 literatures, and only 4 literatures reported it in out-patients (range: 768.0-999.9 CNY), Only one study reported this indicator in inpatients (9 832.0 CNY). One literature reported the total cost per capita of influenza-like illness,, which was 205.1 CNY. And one literature reported that the direct medical cost of inpatients per capita in children under 5 years of age was 6 072.0 CNY while two literature reported this index for the elderly over 60 years of age, ranging from 14 250.0 to 19 349.1 CNY. Four articles reported the economic burden of influenza in urban and rural areas, one of which showed that the related expenses of urban influenza inpatients accounted for 31% of the average annual income, while which for the rural flow was 113%. The average economic burden of lab-confirmed influenza case is higher than that of influenza-like illness, and there are differences in outpatient indirect expenses and inpatients direct medical expenses. The direct medical burden for the hospitalized 60-years-and-beyond influenza case group is heavier thar other age group. By region, the influenza associated individual economic burden in rural area is higher than that of urban area..
了解中国大陆地区流感经济负担的研究现状并总结其主要结果。以“流感”“流行性感冒”“成本”“经济”“负担”“效果”“效益”“效用”“中国”“中文”等词作为检索关键词。检索2000 - 2018年期间发表的期刊论文，检索数据库包括中文电子数据库（中国知网和万方）以及英文电子数据库（PubMed、Web of science、EconLit和Cochrane Library）。文献语言限定为中文和英文。共纳入23篇有效文献，并对文献中的描述性特征、研究指标和方法进行分析。本综述使用的货币单位为人民币（CNY）。23个研究地点主要位于相对发达且人口密集的地区。6篇文献报道了各年龄组实验室确诊流感的人均总成本，仅有4篇文献报道了门诊患者的该指标（范围：768.0 - 999.9元人民币），仅有1项研究报道了住院患者的该指标（9832.0元人民币）。1篇文献报道了流感样疾病的人均总成本，为205.1元人民币。1篇文献报道了5岁以下儿童住院患者的人均直接医疗费用为6072.0元人民币，2篇文献报道了60岁以上老年人的该指标，范围为14250.0至19349.1元人民币。4篇文章报道了城乡流感的经济负担，其中1篇显示城市流感住院患者的相关费用占年均收入的31%，而农村流动人口的该比例为113%。实验室确诊流感病例的平均经济负担高于流感样疾病，门诊间接费用和住院患者直接医疗费用存在差异。60岁及以上流感住院病例组的直接医疗负担比其他年龄组更重。按地区划分，农村地区流感相关的个人经济负担高于城市地区。
