Mĕchurová A, Stípek S, Novák L, Trojan S
Physiol Bohemoslov. 1985;34(2):173-6.
Hypoxia is one of the commonest causes of perinatal morbidity and mortality. The worst affected are tissues with high oxygen consumption, in particular nervous tissue (Trojan 1978). Criteria enabling prompt and reliable evaluation of the length and intensity of hypoxia are therefore being sought (Saugstad 1975a,b, Tuchschmidt et al .1981, O'Connor et al. 1981a,b). In recent years, conflicting information has appeared in the literature on the possibilities of utilizing the hypoxanthine and xanthine level in body fluids as an indicator of oxygen deficiency (Saugstad 1975a, Tuchschmidt et al. 1981). We therefore tested this criterion in newborn infants at risk from intrauterine hypoxia.
缺氧是围产期发病和死亡的最常见原因之一。受影响最严重的是耗氧量高的组织,尤其是神经组织(特洛伊,1978年)。因此,人们一直在寻找能够迅速且可靠地评估缺氧时长和强度的标准(萨格斯塔德,1975年a、b;图施密特等人,1981年;奥康纳等人,1981年a、b)。近年来,文献中出现了关于利用体液中次黄嘌呤和黄嘌呤水平作为缺氧指标的可能性的相互矛盾的信息(萨格斯塔德,1975年a;图施密特等人,1981年)。因此,我们在有宫内缺氧风险的新生儿中测试了这一标准。