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[化学物质及制品中毒]

[Poisoning by chemical substances and products].

作者信息

Begemann Kathrin, Glaser Nina, Desel Herbert

机构信息

Abteilung Exposition, Bundesinstitut für Risikobewertung, Max-Dohrn-Straße 8-10, 10589, Berlin, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Nov;62(11):1346-1353. doi: 10.1007/s00103-019-03033-6.

Abstract

Exposure to chemical substances results in a multitude of poisonings or suspected poisonings every year. Poison centres (PCs) advise the public and medical staff on these issues and register cases in their databases. Additionally, the Federal Institute for Risk Assessment (BfR) maintains a case database with notifications reported by attending physicians within the framework of the Chemicals Act.This article describes important poisons from the field of chemicals and products and gives an example of poisoning risk management for a new product group. For this purpose, exemplary case information published in the annual reports of different PCs and the cases notified to the BfR were examined.An overview is provided on the product groups leading most frequently to poisonings and requests to the PCs. The spectrum of poisonings registered by the BfR and PCs differs clearly between reporting persons, route of exposure and severity. Substance groups with a relatively high risk compared to other chemical substances and products are highly concentrated detergents, acids and alkalis as well as carbon monoxide.PCs and the BfR databases contain valuable information to estimate the frequency and severity of various poisonings. By merging these data in a national poisoning register, new risks would be discovered more quickly in the future and a national overview of poisoning events would be gained.

摘要

每年,接触化学物质都会导致大量中毒或疑似中毒事件。中毒控制中心就这些问题向公众和医务人员提供建议,并将病例登记在其数据库中。此外,联邦风险评估研究所(BfR)维护着一个病例数据库,其中包含执业医师在《化学品法》框架内报告的通知。本文介绍了化学品和产品领域的重要毒物,并给出了一个新产品组中毒风险管理的示例。为此,对不同中毒控制中心年度报告中公布的典型病例信息以及通报给BfR的病例进行了审查。概述了最常导致中毒的产品组以及向中毒控制中心的咨询情况。BfR和中毒控制中心登记的中毒情况在报告人、接触途径和严重程度方面存在明显差异。与其他化学物质和产品相比风险相对较高的物质组包括高浓缩洗涤剂、酸和碱以及一氧化碳。中毒控制中心和BfR的数据库包含有价值的信息,可用于估计各种中毒的频率和严重程度。通过将这些数据合并到一个国家中毒登记册中,未来将能更快地发现新的风险,并获得全国中毒事件的总体情况。

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