检查甘露醇在肾癌手术中的应用：外推手术数据的警示故事。
Examining Mannitol Use in Kidney Cancer Surgery: A Cautionary Tale of Extrapolated Surgical Data.
机构信息
Urology Division, Department of Surgery, Schulich School of Medicine and Dentistry, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada.
Urology Division, Department of Surgery, Schulich School of Medicine and Dentistry, University of Western Ontario, London Health Sciences Centre, London, Ontario, Canada.
出版信息
Eur Urol Focus. 2019 Nov;5(6):930-934. doi: 10.1016/j.euf.2019.09.021. Epub 2019 Oct 15.
Abstract
Mannitol for renal protection during partial nephrectomy is common but unsupported by evidence from clinical trials. The impact of mannitol on renal physiology includes both beneficial and harmful effects. Current understanding of renal ischemia reperfusion injury suggests potentially targetable processes that have a lower potential risk.
摘要
在部分肾切除术中使用甘露醇保护肾脏很常见，但没有临床试验证据支持。甘露醇对肾脏生理的影响既有有益的，也有有害的。目前对肾缺血再灌注损伤的认识表明，可能存在潜在风险较低的可靶向处理过程。
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本文引用的文献
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Intraoperative mannitol during robotic-assisted-laparoscopic partial nephrectomy.机器人辅助腹腔镜部分肾切除术术中甘露醇。
J Robot Surg. 2019 Jun;13(3):401-405. doi: 10.1007/s11701-018-0868-4. Epub 2018 Aug 31.
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