Norström A, Bryman I, Hansson H A
University of Göteborg, Sahlgren's Hospital, Department of Obstetrics and Gynecology, Sweden.
Br J Obstet Gynaecol. 1988 Apr;95(4):372-6. doi: 10.1111/j.1471-0528.1988.tb06608.x.
Twenty women were treated with Lamicel tents for 4 h and 20 women for 16 h before vacuum aspiration in the first trimester of pregnancy. The shorter time of treatment was as effective as the longer time with respect to cervical softening and dilatation. In comparison with an untreated control group, Lamicel treatment was followed by an increased collagenolytic activity and increased sensitivity to prostaglandin E2 of the cervical smooth muscle.
20名女性在妊娠早期进行真空吸引术前使用Lamicel阴道扩张器治疗4小时，另外20名女性治疗16小时。就宫颈软化和扩张而言，较短的治疗时间与较长的治疗时间效果相同。与未治疗的对照组相比，Lamicel治疗后宫颈平滑肌的胶原olytic活性增加，对前列腺素E2的敏感性增加。
