氢化链霉菌的20α-羟基类固醇脱氢酶。
The 20 alpha-hydroxysteroid dehydrogenase of Streptomyces hydrogenans.
作者信息
Rimsay R L, Murphy G W, Martin C J, Orr J C
机构信息
Faculty of Medicine, Health Sciences Centre, Memorial University of Newfoundland, St. John's, Canada.
出版信息
Eur J Biochem. 1988 Jun 1;174(2):437-42. doi: 10.1111/j.1432-1033.1988.tb14117.x.
Abstract
In addition to the well-known 3 alpha,20 beta-hydroxysteroid dehydrogenase ('cortisone reductase'), Streptomyces hydrogenans produces a relatively stable, NAD-dependent 20 alpha-hydroxysteroid dehydrogenase of molecular mass approximately 48 kDa. This enzyme catalyzes the transfer of hydrogen from the 4-pro-S position of NADH.
摘要
除了众所周知的3α,20β-羟基类固醇脱氢酶（“可的松还原酶”）外，氢化链霉菌还产生一种相对稳定的、依赖NAD的20α-羟基类固醇脱氢酶，其分子量约为48 kDa。这种酶催化氢从NADH的4-pro-S位转移。
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