Unit of Orthopaedic Surgery, Department of Public Health, School of Medicine, Federico II University, Naples, Italy.
Department of Infectious Diseases, D. Cotugno Hospital, AORN Dei Colli, Naples, Italy.
BMC Infect Dis. 2019 Oct 24;19(1):887. doi: 10.1186/s12879-019-4556-4.
Arthroscopic partial meniscectomy is a common procedure in orthopedic practice. Infections are uncommon complications of this procedure with an incidence rate of 0,01% - 3,4%. Staphylococcus spp are the predominant causative agents in such cases. We present a case of knee septic arthritis caused by α-hemolytic Streptococcus.
A 22-year-old woman diagnosed with obesity (body mass index [BMI] 35 kg/m) but with no other major comorbidities underwent an arthroscopic selective meniscectomy with administration of intravenous cefazolin for antibiotic prophylaxis. After an uneventful period of 2 months, the patient returned with pain, fever and a discharging sinus at the site of anterolateral arthroscopic portal. Blood tests and magnetic resonance imaging revealed osteomyelitis involving the tibial plate. Cultures of synovial fluid obtained from the knee and a pharyngeal swab yielded α-hemolytic Streptococcus. Five days later, the patient underwent arthroscopic debridement with partial synovectomy. Intraoperative specimens yielded α-hemolytic Streptococcus. The patient received intravenous piperacillin/tazobactam, followed by an associative regimen of amoxicillin and clindamycin with clinical, laboratory and instrumental evidence of symptom resolution.
The incidence of knee septic arthritis after arthroscopic partial meniscectomy is 0.01-3.4%. This infection is usually caused by Staphylococcus spp. and in rare cases by commensal bacteria, such as α-hemolytic streptococci, secondary to transient bacteremia. Screening of the colonized area is important to prevent possible transient bacteremia. Diagnosis is based on isolation of the causative organisms from synovial fluid cultures, and treatment comprises arthroscopic debridement with individualized systemic antibiotic therapy based on the results of an antibiogram.
关节镜下半月板部分切除术是骨科的常见手术。该手术的感染并发症较为少见,发生率为 0.01%-3.4%。金黄色葡萄球菌是此类情况下的主要病原体。我们报告了一例由α-溶血性链球菌引起的膝关节化脓性关节炎。
一名 22 岁女性,患有肥胖症(体重指数 [BMI] 35kg/m),但无其他重大合并症,接受了关节镜选择性半月板切除术,并给予头孢唑啉静脉给药进行抗生素预防。在 2 个月的无并发症期后,患者返回时出现疼痛、发热和前外侧关节镜入口处有窦道排出。血液检查和磁共振成像显示胫骨平台骨髓炎。膝关节滑液和咽拭子培养均培养出α-溶血性链球菌。5 天后,患者接受了关节镜清创术和部分滑膜切除术。术中标本培养出α-溶血性链球菌。患者接受了哌拉西林/他唑巴坦静脉治疗,随后联合使用阿莫西林和克林霉素治疗,临床、实验室和影像学检查均显示症状缓解。
关节镜下半月板部分切除术的膝关节化脓性关节炎发生率为 0.01%-3.4%。这种感染通常由金黄色葡萄球菌引起,在罕见情况下由条件致病菌引起,如α-溶血性链球菌,继发于短暂性菌血症。对定植区域进行筛查对于预防可能的短暂性菌血症很重要。诊断基于从滑膜液培养物中分离出病原体,治疗包括关节镜清创术和根据药敏试验结果个体化全身抗生素治疗。