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从患有坏死性淋巴结炎的野猪分离出的致病性溃疡棒状杆菌菌株的基因组序列。

Genome sequence of a pathogenic Corynebacterium ulcerans strain isolated from a wild boar with necrotizing lymphadenitis.

作者信息

Busch Anne, Möller Jens, Burkovski Andreas, Hotzel Helmut

机构信息

Institut für Bakterielle Infektionen und Zoonosen, Friedrich-Loeffler-Institut, Bundesforschungsinstitut für Tiergesundheit, Jena, Germany.

Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

出版信息

BMC Res Notes. 2019 Oct 25;12(1):692. doi: 10.1186/s13104-019-4704-3.

Abstract

OBJECTIVES

Corynebacterium ulcerans can colonize a wide variety of animals and also humans are infected, typically by zoonotic transmission. Symptoms range from skin ulcers or systemic infections to diphtheria-like illness. In contrast, Corynebacterium pseudotuberculosis is widely distributed among herds of sheep, goats and other farm animals, where it causes high economic losses due to caseous lymphadenitis. Here we describe the genome sequence of an atypical C. ulcerans strain isolated from a wild boar with necrotizing lymphadenitis. This strain has similarities to C. pseudotuberculosis.

DATA DESCRIPTION

Genome sequence data of C. ulcerans isolate W25 were generated, analyzed and taxonomical relationship to other Corynebacterium species as well as growth properties of the isolate were characterized. The genome of C. ulcerans W25 comprises 2,550,924 bp with a G+C content of 54.41% and a total of 2376 genes.

摘要

目的

溃疡棒状杆菌可在多种动物中定殖,人类也会被感染,通常是通过人畜共患病传播。症状范围从皮肤溃疡或全身感染到类白喉疾病。相比之下,伪结核棒状杆菌广泛分布于绵羊、山羊和其他农场动物群体中,在那里它会因干酪性淋巴结炎造成高额经济损失。在此,我们描述了从一头患有坏死性淋巴结炎的野猪中分离出的一株非典型溃疡棒状杆菌菌株的基因组序列。该菌株与伪结核棒状杆菌有相似之处。

数据描述

生成了溃疡棒状杆菌分离株W25的基因组序列数据,对其进行了分析,并确定了它与其他棒状杆菌属物种的分类关系,同时还对该分离株的生长特性进行了表征。溃疡棒状杆菌W25的基因组由2,550,924个碱基对组成,G+C含量为54.41%,共有2376个基因。

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