Scotti Katherine Maria, Koenigshof Amy, Sri-Jayantha Loren S H, Kato Michael, Bishop Micah, Barr James W, Pashmakova Medora B
Michigan State University Veterinary Medical Center, East Lansing, Missouri.
Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts.
J Vet Emerg Crit Care (San Antonio). 2019 Nov;29(6):647-652. doi: 10.1111/vec.12896. Epub 2019 Oct 26.
To identify physical exam findings, clinicopathological parameters, time to surgery, empirical antimicrobial use, and culture results that could be associated with outcome in cats with septic peritonitis (SP).
Retrospective cohort study of cats from 2002 to 2015.
Four university teaching hospitals.
Eighty-three cats diagnosed with SP by cytology or culture.
None MEASUREMENTS AND MAIN RESULTS: Fifty-eight cats survived to discharge (69.9%); 1 cat was euthanized in surgery; 20 were euthanized postoperatively; 4 cats suffered cardiac arrest after surgery. The most common etiology of SP was secondary SP due to gastrointestinal perforation (49.4%), followed by primary SP (22.3%). Mean blood glucose concentration was significantly different between survivors and nonsurvivors (P = 0.006). Cats that received appropriate empirical antibiotic therapy were 4.4 times more likely to survive than cats that did not receive appropriate antibiotics (P = 0.018).
As previously documented, SP secondary to gastrointestinal leakage was the most common etiology. In this population, cats with a higher blood glucose concentration on presentation had a worse prognosis. Cats that received appropriate empirical antimicrobial therapy were more likely to survive.
确定与猫脓毒症性腹膜炎(SP)预后相关的体格检查结果、临床病理参数、手术时间、经验性抗菌药物使用情况及培养结果。
对2002年至2015年的猫进行回顾性队列研究。
四家大学教学医院。
83只经细胞学或培养确诊为SP的猫。
无
58只猫存活至出院(69.9%);1只猫在手术中实施安乐死;20只猫术后实施安乐死;4只猫术后发生心脏骤停。SP最常见的病因是继发于胃肠道穿孔的继发性SP(49.4%),其次是原发性SP(22.3%)。存活猫与非存活猫的平均血糖浓度有显著差异(P = 0.006)。接受适当经验性抗生素治疗的猫存活可能性是非适当抗生素治疗猫的4.4倍(P = 0.018)。
如先前文献记载,继发于胃肠道渗漏的SP是最常见病因。在本研究群体中,就诊时血糖浓度较高的猫预后较差。接受适当经验性抗菌治疗的猫更有可能存活。