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利钠肽检测在疑似急性心力衰竭患者评估中的应用价值。

A value proposition for natriuretic peptide measurement in the assessment of patients with suspected acute heart failure.

机构信息

Clinical Chemistry Laboratory, Altnagelvin Hospital, Londonderry, N. Ireland, UK; Centre for Personalised Medicine: Clinical Decision Making and Patient Safety, C-TRIC, Altnagelvin Hospital, Londonderry, N. Ireland, UK.

Clinical Chemistry Laboratory, Altnagelvin Hospital, Londonderry, N. Ireland, UK; Centre for Personalised Medicine: Clinical Decision Making and Patient Safety, C-TRIC, Altnagelvin Hospital, Londonderry, N. Ireland, UK.

出版信息

Clin Chim Acta. 2020 Jan;500:98-103. doi: 10.1016/j.cca.2019.09.023. Epub 2019 Oct 23.

Abstract

There is robust clinical trial evidence supporting the role of natriuretic peptides [NPs] in the assessment of patients presenting with suspected acute heart failure [AHF]. Despite the fact that clinical guidelines have for some time advocated NP measurement, the availability and uptake of NP testing in acute care services remains patchy and incomplete. The reasons for this are multifactorial but are underpinned by compartmentalised management and budget structures within complex healthcare delivery organisations. This paper outlines a value proposition for NP testing in the acute care setting which crosses the continuum of services and budgets. It articulates the expected benefits to each stakeholder in terms of efficiency of processes, clinical outcomes and cost effectiveness. It describes a pathway to implementation and suggests metrics that may be used to measure the effectiveness of introduction of NP testing. It is hoped that the value proposition will facilitate the uptake of NT testing fostering collaboration between laboratory, clinical, management and finance teams and by informing the development of business cases.

摘要

有大量的临床试验证据支持利钠肽(NPs)在评估疑似急性心力衰竭(AHF)患者中的作用。尽管临床指南已经提倡一段时间的 NP 测量,但在急性护理服务中,NP 检测的可用性和采用仍然参差不齐且不完整。造成这种情况的原因是多方面的,但在复杂的医疗保健提供组织中,管理和预算结构是支离破碎的。本文概述了在急性护理环境中进行 NP 检测的价值主张,该主张跨越了服务和预算的连续体。它阐述了每个利益相关者在流程效率、临床结果和成本效益方面的预期收益。它描述了实施的途径,并提出了可能用于衡量 NP 检测引入效果的指标。希望该价值主张将促进 NP 检测的采用,促进实验室、临床、管理和财务团队之间的合作,并为制定商业案例提供信息。

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