Sait S N, Brecher M L, Green D M, Sandberg A A
Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Cancer Genet Cytogenet. 1988 Sep;34(2):277-80. doi: 10.1016/0165-4608(88)90273-7.
Acquired chromosomal abnormalities have been reported in 80 patients with congenital acute leukemia, the commonest being t(4;11). We report here a case of acute megakaryocytic leukemia with a rare translocation of t(1;22)(p13.3;q13.3). The course of the disease was short, with the patient surviving less than a year after the initial diagnosis.
