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神经病变可能是糖尿病成人下肢烧伤后截肢的独立危险因素。

Neuropathy May Be an Independent Risk Factor for Amputation After Lower-Extremity Burn in Adults With Diabetes.

作者信息

Sen Soman, Barsun Alura, Romanowski Kathleen, Palmieri Tina, Greenhalgh David

机构信息

Department of Surgery, Division of Burn Surgery, University of California Davis, Sacramento, CA.

出版信息

Clin Diabetes. 2019 Oct;37(4):352-356. doi: 10.2337/cd18-0066.

DOI:10.2337/cd18-0066
PMID:31660008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6794228/
Abstract

Treatment of lower-extremity burn injuries in adults with diabetes can be complex, and some diabetes-related factors can lead to impaired healing of such wounds, putting patients at risk of amputation. In this retrospective review of adult patients with lower-extremity burns, patients with pre-injury neuropathy and higher A1C levels were more likely to require amputations after their burn injury. The authors conclude that lower-extremity burn injuries in patients with diabetes require close follow-up and possibly referral to a burn specialist for interventions and treatment strategies to offset more serious complications.

摘要

糖尿病成人患者下肢烧伤的治疗可能很复杂,一些与糖尿病相关的因素会导致此类伤口愈合受损,使患者面临截肢风险。在这项对成人下肢烧伤患者的回顾性研究中,伤前患有神经病变且糖化血红蛋白(A1C)水平较高的患者在烧伤后更有可能需要截肢。作者得出结论,糖尿病患者的下肢烧伤需要密切随访,可能还需转诊至烧伤专科医生处,以采取干预措施和治疗策略来避免更严重的并发症。

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Neuropathy May Be an Independent Risk Factor for Amputation After Lower-Extremity Burn in Adults With Diabetes.神经病变可能是糖尿病成人下肢烧伤后截肢的独立危险因素。
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本文引用的文献

1
Hemoglobin A1c Testing and Amputation Rates in Black, Hispanic, and White Medicare Patients.黑人、西班牙裔和白人医疗保险患者的糖化血红蛋白检测与截肢率
Ann Vasc Surg. 2016 Oct;36:208-217. doi: 10.1016/j.avsg.2016.03.035. Epub 2016 Jul 27.
2
Increased admissions for diabetes mellitus after burn.烧伤后糖尿病入院人数增加。
Burns. 2016 Dec;42(8):1734-1739. doi: 10.1016/j.burns.2016.06.005. Epub 2016 Jun 20.
3
Glucose control and diabetic neuropathy: lessons from recent large clinical trials.血糖控制与糖尿病神经病变:近期大型临床试验的经验教训
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Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights.糖尿病患者伤口愈合受损的发病机制与治疗:新见解
Adv Ther. 2014 Aug;31(8):817-36. doi: 10.1007/s12325-014-0140-x. Epub 2014 Jul 29.
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Diabetic neuropathy: mechanisms, emerging treatments, and subtypes.糖尿病性神经病变:发病机制、新兴治疗方法及亚型
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Impact of diabetes and comorbidities on split-thickness skin grafts for foot wounds.糖尿病及合并症对足部伤口的中厚皮片移植的影响。
J Am Podiatr Med Assoc. 2013 May-Jun;103(3):223-32. doi: 10.7547/1030223.
7
Utility of screening for diabetes in a burn center: hemoglobin A1c, Diabetes Risk Test, or simple history?烧伤中心糖尿病筛查的效用:糖化血红蛋白、糖尿病风险测试还是简单病史?
Burns. 2013 Aug;39(5):881-4. doi: 10.1016/j.burns.2012.10.009. Epub 2012 Dec 27.
8
A ten-year review of lower extremity burns in diabetics: small burns that lead to major problems.糖尿病患者下肢烧伤的十年回顾:小面积烧伤引发重大问题
J Burn Care Res. 2013 Mar-Apr;34(2):255-60. doi: 10.1097/BCR.0b013e318257d85b.
9
Abnormal regulation of neo-vascularisation in deep partial thickness scalds in rats with diabetes mellitus.糖尿病大鼠深Ⅱ度烫伤创面新生血管异常调控。
Burns. 2011 Sep;37(6):1015-22. doi: 10.1016/j.burns.2011.03.020.
10
Impact of diabetes on burn injury: preliminary results from prospective study.糖尿病对烧伤的影响:前瞻性研究的初步结果。
J Burn Care Res. 2011 May-Jun;32(3):435-41. doi: 10.1097/BCR.0b013e318217f954.