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基于镜像神经元理论的动作观察疗法对脑卒中后言语失用症中国患者的疗效。

The Effectiveness of Action Observation Therapy Based on Mirror Neuron Theory in Chinese Patients with Apraxia of Speech after Stroke.

机构信息

Department of Rehabilitation, Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China.

Department of Rehabilitation Zhongda Hospital Southeast University, Nanjing, China.

出版信息

Eur Neurol. 2019;81(5-6):278-286. doi: 10.1159/000503960. Epub 2019 Oct 29.

Abstract

OBJECTIVE

The present study aimed to evaluate the efficacy of action observation therapy (AOT) on apraxia of speech (AOS) in patients after stroke.

MATERIALS AND METHODS

Forty-two patients diagnosed with AOS after stroke were randomly divided into an experimental group (n = 21) and a control group (n = 21). Both groups received 30 min of conventional language therapy twice daily, 5 days a week for 4 weeks. The patients in the experimental group additionally received 20 min of AOT before 10 min language therapy each day. The speech function and aphasia severity of the 2 groups were assessed using the speech apraxia assessment method of the China Rehabilitation Research Center, Western Aphasia Battery (WAB), and the Boston Diagnostic Aphasia Examination before and after treatment.

RESULTS

AOS and WAB scores increased significantly after treatment in both groups (p < 0.05). AOS and WAB scores exhibited significant differences between the experimental group and the control group after training (p < 0.05). The response rate in the experimental group was significantly higher than that in the control group (p < 0.05).

CONCLUSION

AOT based on mirror neuron theory may improve language function in patients with AOS after stroke.

摘要

目的

本研究旨在评估动作观察疗法(AOT)对脑卒中后言语失用症(AOS)患者的疗效。

材料与方法

42 例脑卒中后诊断为 AOS 的患者被随机分为实验组(n=21)和对照组(n=21)。两组均接受每日 2 次、每次 30 分钟的常规语言治疗,每周 5 天,持续 4 周。实验组患者在每日 10 分钟语言治疗前额外接受 20 分钟 AOT。治疗前后采用中国康复研究中心言语失用评估方法、西方失语症成套测验(WAB)和波士顿诊断性失语症检查评估两组患者的言语功能和失语症严重程度。

结果

两组治疗后 AOS 和 WAB 评分均显著升高(p<0.05)。训练后实验组与对照组 AOS 和 WAB 评分差异有统计学意义(p<0.05)。实验组的反应率显著高于对照组(p<0.05)。

结论

基于镜像神经元理论的 AOT 可能改善脑卒中后 AOS 患者的语言功能。

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