Division of Veterinary Clinical Studies, The Royal (Dick) School of Veterinary Studies and The Roslin Institute, Roslin, UK
Division of Veterinary Clinical Studies, The Royal (Dick) School of Veterinary Studies and The Roslin Institute, Roslin, UK.
Vet Rec. 2020 Jan 4;186(1):26. doi: 10.1136/vr.105172. Epub 2019 Oct 29.
Chronic enteropathies (CEs) are a common cause of morbidity in dogs. CEs are diagnosed in dogs with chronic gastrointestinal clinical signs (>3 weeks), inflammatory changes on intestinal biopsies and where no other underlying cause is determined based on a thorough, standardised diagnostic work-up. Based on response to therapy, CEs are subclassified into food-responsive, antibiotic-responsive or steroid-responsive enteropathies. A significant proportion of dogs with a CE are food-responsive; however, there are limited peer-reviewed publications describing the clinical efficacy of the commercially available diets used to treat CE.
In this study, the authors evaluated the response of 15 dogs with a CE to a commercially available dietetic food (Hill's Prescription Diet i/d Sensitive Canine Dry). The dogs underwent a standard diagnostic evaluation and did not receive concurrent anthelmintic, antibiotic, glucocorticoid or gastroprotectant therapies. The clinical efficacy of the dietary treatment was assessed by comparing the Canine Inflammatory Bowel Disease Activity Index (CIBDAI) before and a median of 13 days after dietary therapy.
The authors found that the CIBDAI significantly decreased following the introduction of the dietetic food (median CIBDAI score pretreatment 9, post-treatment 2; P<0.0005).
This study demonstrates that this dietetic food can be used to successfully manage CE in dogs.
慢性肠病（CEs）是犬类发病的常见原因。CEs 被诊断为患有慢性胃肠道临床症状（>3 周）、肠活检有炎症变化且在全面、标准化诊断后未发现其他潜在病因的犬。根据治疗反应，CE 可分为食物反应性、抗生素反应性或皮质类固醇反应性肠病。尽管有相当一部分患有 CE 的犬对食物有反应，但描述用于治疗 CE 的市售饮食的临床疗效的同行评审出版物有限。
在这项研究中，作者评估了 15 只患有 CE 的犬对市售饮食（希尔斯处方饮食 i/d 敏感犬干粮）的反应。这些犬接受了标准诊断评估，并未同时接受驱虫药、抗生素、皮质类固醇或胃保护剂治疗。通过比较饮食治疗前后中位 13 天的犬炎症性肠病活动指数（CIBDAI），评估饮食治疗的临床疗效。
作者发现，引入饮食后 CIBDAI 显著降低（治疗前 CIBDAI 中位数为 9，治疗后为 2；P<0.0005）。
这项研究表明，这种饮食可以成功地用于管理犬类的 CE。
