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氚暴露人员的医学治疗与剂量估算

Medical Treatment and Dose Estimation of a Person Exposed to Tritium.

作者信息

Chen Weibo, Li Houwen, Wang Kongzhao, Bian Huahui, Wang Youyou, Cui Fengmei, Liu Yulong, Chen Qiu

机构信息

Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China.

CNNP Nuclear Power Operations Management Co, Ltd, Haiyan, ZheJiang, China.

出版信息

Dose Response. 2019 Oct 15;17(4):1559325819880670. doi: 10.1177/1559325819880670. eCollection 2019 Oct-Dec.

Abstract

In this study, we aimed to investigate the damaging effects and clinical therapy of internal contamination with tritium to provide information and gain experience for medical treatments in case of an emergency due to a nuclear accident. Histories were taken by several doctors who observed and recorded the clinical symptoms of the patient described herein. The general health situation was evaluated by laboratory and equipment analyses. Tritium concentrations in the urine were estimated according to relevant standards during the monitoring period using a liquid scintillation counting method. Clinical observation revealed that the patient had symptoms of mild asthenia and sleep disorder with improvement after appropriate treatment. The last committed effective dose was determined through measurement of the urine tritium concentration and dose estimation and was estimated to be 0.123 mSv; the total effective dose was 14.536 mSv. The medical treatment and dose estimation in this patient with tritium contamination were successful and can provide a reference for similar cases in the future.

摘要

在本研究中,我们旨在调查氚内污染的损害作用及临床治疗方法,以便在核事故紧急情况下为医疗救治提供信息并积累经验。由几位医生询问病史,他们观察并记录了本文所述患者的临床症状。通过实验室检查和设备分析评估总体健康状况。在监测期间,采用液体闪烁计数法根据相关标准估算尿中氚浓度。临床观察发现,该患者有轻度乏力和睡眠障碍症状,经适当治疗后有所改善。通过测量尿氚浓度和剂量估算确定了最后一次待积有效剂量,估计为0.123毫希沃特;总有效剂量为14.536毫希沃特。该例氚污染患者的医疗救治及剂量估算取得成功,可为今后类似病例提供参考。

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本文引用的文献

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Effects of Chahuangjing on Decorporation and Radiation Protection Against Tritiated Water.茶黄素对氚水促排及辐射防护的作用
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J Res Natl Inst Stand Technol. 2000 Aug 1;105(4):541-9. doi: 10.6028/jres.105.043. Print 2000 Jul-Aug.
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Distribution of tritium in estuarine waters: the role of organic matter.氚在河口水中的分布:有机物的作用。
J Environ Radioact. 2009 Oct;100(10):890-5. doi: 10.1016/j.jenvrad.2009.06.018. Epub 2009 Jul 15.
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J Environ Radioact. 2009 Jul;100(7):558-63. doi: 10.1016/j.jenvrad.2009.03.020. Epub 2009 May 5.
6
Applying direct liquid scintillation counting to low level tritium measurement.将直接液体闪烁计数法应用于低水平氚测量。
Appl Radiat Isot. 2009 May;67(5):812-6. doi: 10.1016/j.apradiso.2009.01.023. Epub 2009 Jan 23.
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Appl Radiat Isot. 1999 Feb;50(2):311-6. doi: 10.1016/s0969-8043(97)10153-1.

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