Internal Clinic Laplje Selo, Clinical Hospital Center Pristina-Gracanica, Prishtina, Serbia.
Pulomonology Clinic, Clinical Hospital Center Pristina-Gracanica, Prishtina, Serbia.
Pain Res Manag. 2019 Sep 29;2019:7684762. doi: 10.1155/2019/7684762. eCollection 2019.
The aim of this study was to analyse the relationship between the clinical manifestations, disease severity based on radiography images, functional activity level, and quality of life in patients with knee osteoarthritis in a rural population living in Serbian enclaves in Kosovo, as well as to determine the correlation between the WOMAC and the EQ-5D questionnaire in this population.
The cross-sectional study was conducted at the Internal Medicine Clinic, Clinical Hospital Center Pristina-Gracanica, located in Laplje Selo from February to December 2013. One hundred patients with confirmed (American College of Rheumatology criteria) knee osteoarthritis completed the EQ-5D and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaires, rated pain on a visual analogue scale (VAS), and underwent knee radiographic examinations.
Most patients were obese with moderate radiographic changes according to the Kellgeren-Lawrence scale and suffered from very severe pain according to the VAS scale. The duration of disease significantly correlated with the WOMAC scores, VAS score, and all of the scores on the EQ-5D, except for mobility. The age of participants showed a similar correlation with the same variables. The patients with higher Kellgren-Lawrence scores (3-4) were significantly older, with a significantly higher body mass index (BMI) and longer duration of disease than patients with lower scores (1-2). Significantly higher VAS, pain/discomfort EQ-5D, and WOMAC pain and function scores were also recorded among patients with more significant radiological changes. The correlations between WOMAC and EQ-5D were satisfactory.
The severity of clinical manifestations and radiographic area changes may affect functional ability and the quality of life in knee OA patients living in rural areas, which requires adequate treatment and physical therapy.
本研究旨在分析塞尔维亚科索沃飞地农村地区膝骨关节炎患者的临床表现、基于影像学的疾病严重程度、功能活动水平和生活质量之间的关系,并确定该人群中 WOMAC 和 EQ-5D 问卷之间的相关性。
这项横断面研究于 2013 年 2 月至 12 月在位于 Laplje Selo 的普里什蒂纳-格拉查尼察临床中心内科诊所进行。100 名确诊(美国风湿病学会标准)膝骨关节炎患者完成了 EQ-5D 和西安大略和麦克马斯特大学骨关节炎指数(WOMAC)问卷,对疼痛进行视觉模拟评分(VAS),并进行了膝关节影像学检查。
大多数患者肥胖,根据 Kellgeren-Lawrence 量表有中度影像学改变,根据 VAS 量表有严重疼痛。疾病持续时间与 WOMAC 评分、VAS 评分和 EQ-5D 的所有评分显著相关,但与移动性无关。参与者的年龄与相同变量也显示出类似的相关性。Kellgren-Lawrence 评分较高(3-4)的患者年龄明显较大,体重指数(BMI)明显较高,疾病持续时间也明显较长评分较低(1-2)的患者。影像学变化较大的患者的 VAS、疼痛/不适 EQ-5D 和 WOMAC 疼痛和功能评分也明显较高。WOMAC 和 EQ-5D 之间的相关性令人满意。
临床表现和影像学区域变化的严重程度可能会影响农村地区膝骨关节炎患者的功能能力和生活质量,这需要进行适当的治疗和物理治疗。