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超低位剂量 CT:输尿管结石的有效随访成像方式。

Ultra-Low-Dose CT: An Effective Follow-Up Imaging Modality for Ureterolithiasis.

机构信息

Department of Urology, Stanford University School of Medicine, Stanford, California.

Department of Nephrology, Stanford University School of Medicine, Stanford, California.

出版信息

J Endourol. 2020 Feb;34(2):139-144. doi: 10.1089/end.2019.0574. Epub 2020 Jan 10.

Abstract

Classically, abdominal X-ray (KUB), ultrasound, or a combination of both have been routinely used for ureteral stone surveillance after initial diagnosis. More recently, ultra-low-dose CT (ULD CT) has emerged as a CT technique that reduces radiation dose while maintaining high sensitivity and specificity for urinary stone detection. We aim to evaluate our initial experience with ULD CT for patients with ureterolithiasis, measuring real-world radiation doses and stone detection performance. We reviewed all ULD CT scans performed at the Veterans Affairs Palo Alto Health Care System between 2016 and 2018. We included patients with ureteral stones and calculated the mean effective radiation dose per scan. We determined stone location and size, if the stone was visible on the associated KUB or CT scout film, and if hydronephrosis was present. We performed logistic regression to identify variables associated with visibility on KUB or CT scout film and hydronephrosis. One hundred eighteen ULD scans were reviewed, of which 50 detected ureteral stones. The mean effective radiation dose was 1.04 ± 0.41 mSv. Of the ULD CTs that detected ureterolithiasis, 38% lacked visibility on KUB/CT scout film and had no associated hydronephrosis, suggesting that they would be missed with a combination of KUB and ultrasound. Larger stones (odds ratio [OR]: 1.40, 95% confidence interval [CI]: 1.08, 1.96 for every 1 mm increase in stone size) were more likely to be detected by KUB/CT scout film or ultrasound, while stones in the distal ureter (OR: 0.18, 95% CI: 0.03, 0.81) were more likely to be missed by KUB/CT scout film or hydronephrosis. Based on our institutions' initial experience, ULD CT detects small and distal ureteral stones that would likely be missed by KUB or ultrasound, while maintaining a low effective radiation dose. An ULD CT protocol should be considered when reimaging for ureteral stones is necessary.

摘要

经典的方法是,在初始诊断后,通过腹部 X 射线(KUB)、超声或两者结合,对输尿管结石进行常规监测。最近,超低剂量 CT(ULD CT)作为一种 CT 技术出现,它在保持高灵敏度和特异性检测尿路结石的同时,降低了辐射剂量。我们旨在评估 ULD CT 在输尿管结石患者中的初步应用经验,测量实际辐射剂量和结石检出性能。

我们回顾了 2016 年至 2018 年期间在退伍军人事务帕洛阿尔托医疗保健系统进行的所有 ULD CT 扫描。我们纳入了有输尿管结石的患者,并计算了每次扫描的平均有效辐射剂量。我们确定了结石的位置和大小,如果结石在相关的 KUB 或 CT 扫描片上可见,如果存在肾积水。我们进行了逻辑回归分析,以确定与 KUB 或 CT 扫描片可见性和肾积水相关的变量。

共回顾了 118 次 ULD 扫描,其中 50 次发现输尿管结石。平均有效辐射剂量为 1.04±0.41 mSv。在检测到输尿管结石的 ULD CT 中,38%在 KUB/CT 扫描片上不可见,也没有相关的肾积水,这表明如果仅使用 KUB 和超声,这些结石可能会被漏诊。较大的结石(OR:1.40,95%CI:1.08,1.96,每增加 1mm 结石大小)更有可能通过 KUB/CT 扫描片或超声检测到,而输尿管下段的结石(OR:0.18,95%CI:0.03,0.81)更有可能通过 KUB/CT 扫描片或肾积水漏诊。

根据我们机构的初步经验,ULD CT 可检测到 KUB 或超声可能漏诊的小结石和输尿管下段结石,同时保持低有效辐射剂量。当需要对输尿管结石进行再次成像时,应考虑使用 ULD CT 方案。

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