In the Department of Dermatology, University of Texas Medical Branch at Galveston, Keith D. Wagner, MD, MS, is a resident physician; Kate Woolridge, MD, is a dermatology resident graduate; and Ashley Group, MD, is Associate Professor of Dermatology.
Adv Skin Wound Care. 2019 Dec;32(12):553-557. doi: 10.1097/01.ASW.0000582636.98643.3b.
Digital ulcers are a serious complication in 50% of patients with scleroderma. These ulcers have the potential to resist conventional therapies. There have been several reviews of scleroderma care over the last 5 years, but there are new developments in this field that advance clinician knowledge. This review provides an overview of previous digital ulcer management and a concise summary of new peer-reviewed literature on the topic since 2015 to provide guidance to practitioners and researchers seeking well-supported and novel/off-label therapies to consider.
硬皮病患者中有 50%会出现严重的手指溃疡并发症。这些溃疡可能对常规治疗产生抗药性。在过去 5 年中，有多项关于硬皮病护理的综述，但该领域仍有新的进展，可提高临床医生的认知。本文综述了以往的手指溃疡管理方法，并简明扼要地总结了 2015 年以来该领域新的同行评议文献，为寻求有充分依据且新颖/超适应证治疗方法的从业者和研究人员提供指导。
