Kochubeev G A, Frolov A A, Kostiuk V A, Pronskaia I V, Gurinovich G P
Biofizika. 1988 May-Jun;33(3):471-4.
Photodestruction of erythrocyte membranes sensitized by water soluble chlorophyll derivative chlorine e6 (Chl e6) was studied. It has been determined that light irradiation of erythrocyte ghosts with wave length lambda-660 nm in the presence of Chl e6 caused in protein and lipid components of the membrane deep destructive changes which were expressed in cross-linking of the membrane polypeptides and accumulating in the membrane products of peroxidation of unsaturated fatty acids residues, in phospholipids mainly. It has been shown that these processes were realized only in the presence of molecular oxygen and consequently possess pure photodynamic character.
研究了水溶性叶绿素衍生物氯e6（Chl e6）致敏的红细胞膜的光破坏作用。已确定，在Chl e6存在下，用波长λ-660nm的光照射红细胞血影，会导致膜的蛋白质和脂质成分发生深度破坏变化，表现为膜多肽交联以及不饱和脂肪酸残基过氧化产物在膜中积累，主要是在磷脂中。已表明这些过程仅在分子氧存在下才会发生，因此具有纯光动力特性。
