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全髋关节置换术后常发生类似坏死性筋膜炎的空气栓塞。

Air entrapment resembling necrotising fasciitis as a frequent incident following total hip arthroplasty.

机构信息

Department of Orthopaedics and Trauma, Medical University of Graz, Graz, Austria.

出版信息

Sci Rep. 2019 Oct 31;9(1):15766. doi: 10.1038/s41598-019-52113-9.

Abstract

In combination with pain and elevated inflammatory parameters that are frequently observed following elective total hip arthroplasty (THA), air entrapment on radiographic images could be indicative of necrotising fasciitis. The aim of the present study was to analyse presence/extent of air entrapment following THA, and to correlate radiological with clinical findings. One-hundred patients undergoing short-stem elective THA (ANA NOVA Alpha Proxy-system) were prospectively included. Patients received pre- and postoperative x-rays (day 1 + discharge) of the affected hip, together with a CT-scan of the lower extremity (discharge). C-reactive-protein-(CRP), leukocyte, haemoglobin-, creatinine-, glucose-, sodium-levels - and based on these the LRINEC score- as well as pain-scores (numeral-rating-scale, NRS) at postoperative days 1, 3 and 5 were documented. Air entrapment was visible in 98% of x-rays taken postoperatively and in 93% of CT-scans at discharge. Leukocyte-levels significantly decreased from postoperative day 1 to 5. CRP-levels had a peak at the 3 postoperative day (p < 0.001). On discharge-x-rays of patients with low body-mass-indexes, air entrapment was significantly more often visible (p = 0.040). Neither implant-related nor laboratory parameters, LRINEC- or NRS-scores significantly correlated with presence/extent of air entrapment (p > 0.05). Considering the high rate of air entrapment following elective THA postoperatively and at discharge, suspicion of an infection with gas-producing bacteria may only be raised in case of persistent inflammatory parameters, deteriorating general condition and signs of local infection.

摘要

在择期全髋关节置换术(THA)后常观察到疼痛和炎症参数升高,影像学上的空气滞留可能提示坏死性筋膜炎。本研究旨在分析 THA 后空气滞留的存在/程度,并将影像学与临床发现进行相关性分析。前瞻性纳入了 100 例行短柄择期 THA(ANA NOVA Alpha Proxy 系统)的患者。患者在术后第 1 天(+出院)和受影响的髋关节接受 X 射线检查,并在出院时进行下肢 CT 扫描。记录术后第 1、3 和 5 天的 C 反应蛋白(CRP)、白细胞、血红蛋白、肌酐、血糖、钠水平以及基于这些的 LRINEC 评分和疼痛评分(数字评分量表,NRS)。术后 X 射线检查中 98%可观察到空气滞留,出院时 CT 扫描中 93%可观察到空气滞留。白细胞计数从术后第 1 天到第 5 天显著下降。CRP 水平在术后第 3 天达到峰值(p<0.001)。在低体重指数患者的出院 X 射线中,空气滞留更常可见(p=0.040)。与空气滞留的存在/程度无显著相关的是与植入物相关或实验室参数、LRINEC 评分或 NRS 评分(p>0.05)。考虑到择期 THA 术后和出院时空气滞留的发生率较高,只有在持续的炎症参数、一般状况恶化和局部感染迹象的情况下,才应怀疑存在产气细菌感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f58/6823472/7c90cde782c4/41598_2019_52113_Fig1_HTML.jpg

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