Department of Dermatology, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Department of Dermatology, Yanbian University Hospital, Yanji, China.
J Dermatol. 2020 Jan;47(1):72-77. doi: 10.1111/1346-8138.15129. Epub 2019 Oct 31.
Even after complete removal with Mohs micrographic surgery (MMS), cutaneous squamous cell carcinoma (cSCC) may recur; however, information about risk factors for recurrence in Asian patients is limited. This retrospective study reviewed cSCC patients treated with MMS at a single tertiary referral center from 2000 to 2017. Two hundred and thirty-seven patients were included and 36 showed recurrence (20 with local recurrence, 16 with distant metastasis). History of organ transplantation, diabetes, other malignancies and poorly differentiated histology correlated with cSCC recurrence. History of organ transplantation and cryotherapy at the cSCC site were related to higher local recurrence rates, and poor differentiation related to higher distant metastasis in Asian cSCC patients treated with MMS.
即使经过 Mohs 显微外科手术（MMS）的完全切除，皮肤鳞状细胞癌（cSCC）仍可能复发；然而，有关亚洲患者复发风险因素的信息有限。本回顾性研究分析了 2000 年至 2017 年在一家三级转诊中心接受 MMS 治疗的 cSCC 患者。共纳入 237 例患者，其中 36 例出现复发（20 例局部复发，16 例远处转移）。器官移植史、糖尿病、其他恶性肿瘤和低分化组织学与 cSCC 复发相关。亚洲 MMS 治疗的 cSCC 患者中，器官移植史和 cSCC 部位冷冻治疗与更高的局部复发率相关，而分化不良与更高的远处转移率相关。
